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Nanogel star polymers are developed as a new route for the formation of dual‐mode nanoparticle systems for applications in the areas of synergistic therapeutic delivery, imaged therapeutic delivery, and dual‐mode bioimaging agents. These extremely uniform, structurally versatile, water‐soluble, unimolecular organic nanoparticles with tunable polyvalency and functionality are preprogrammed to spontaneously...
On page 4509, Robert D. Miller, Joseph Sly, and co‐workers report the use of sequential polymer synthesis to create highly uniform, size‐controlled nanogel star polymer nanoparticles capable of programmable tandem‐modal self‐assembly with other functional molecules and transportation of their “cargo” across cellular membranes. These dual‐mode unimolecular delivery vehicles have been developed for...
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