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Cell‐laden hydrogels used in tissue engineering generally lack sufficient 3D topographical guidance for cells to mature into aligned tissues. A new strategy called filamented light (FLight) biofabrication rapidly creates hydrogels composed of unidirectional microfilament networks, with diameters on the length scale of single cells. Due to optical modulation instability, a light beam is divided optically...
Biofabrication
In article number 2204301, Marcy Zenobi‐Wong and co‐workers use Filamented Light (FLight) biofabrication to create hydrogel constructs containing ultrahigh‐aspect‐ratio microfilaments. FLight biofabrication is both fast and biocompatible. Microfilaments and associated microchannels provide effective topological guidance cues to instruct cell migration, alignment, and extracellular matrix...