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Adenosine triphosphate (ATP) can be released in large amounts from (damaged) cells, leading to locally high concentrations. In this study, we investigated the effect of such high concentrations of ATP on neuroblastoma cells. ATP (=<30μM) induced apoptosis in the mouse neuroblastoma cell line N1E-115. Activation of the ATP receptor P2X 7 is one of the routes via which ATP has been shown...
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