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Temozolomide, a new oral cytotoxic agent, was given to 75 patients with malignant gliomas. The schedule used was for the first course 150 mg/m 2 per day for 5 days (i.e. total dose 750 mg/m 2 ), escalating, if no significant myelosuppression was noted on day 22, to 200 mg/m 2 per day for 5 days (i.e. total dose 1000 mg/m 2 ) for subsequent courses at 4-week intervals...
Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.