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Immune cells deeply affect human health, however, it has not been investigated well due to difficulty of observing immune cells in vivo. The recent study enables us to acquire single Macrophage, which is the representative cell of immune cells, in vivo using 11.7 T magnetic resonance imaging (MRI). To quantify the kinematics of macrophages, it requires detection and tracking macrophages in MR image...
Near-infrared (NIR) fluorescence imaging has become an important modality for the non-invasive imaging of living tissues because of its low absorption and scattering. Although NIR fluorescence imaging has the capability of non-invasive deep tissue imaging with a low auto-fluorescence, its spatial resolution is not enough to show a three-dimensional object's location with an anatomical resolution....
Macrophage is one of white blood cells, and plays an important role of the immune system. Tracking the single macrophage cells in vivo will be a powerful tool for immunology studies. State-of-the-arts imaging using magnetic resonance imaging (MRI) enables us to acquire images of 3-D dynamic single macrophage cells in vivo. However, due to motion artifacts and magnetic field fluctuations, a post-processing...
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