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Induction of stress proteins in response to heat shock was found to be reduced significantly in Escherichia coli with ΔtopA mutation. RNase H overexpression in the ΔtopA mutant partially restored the σ 32 -dependent induction of stress genes in response to high temperature and ethanol. The presence of overexpressed RNase H also improved the survival rate of the ΔtopA mutant after high...
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