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Autotaxin (ATX or ENPP2) is a secreted glycosylated mammalian enzyme that exhibits lysophospholipase D activity, hydrolyzing lysophosphatidylcholine to the signalling lipid lysophosphatidic acid. ATX is an ∼100 kDa multi‐domain protein encompassing two N‐terminal somatomedin B‐like domains, a central catalytic phosphodiesterase domain and a C‐terminal nuclease‐like domain. Protocols for the efficient...
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