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Background: Aquifex aeolicus Ribonuclease III (Aa-RNase III) belongs to the family of Mg 2+ -dependent endonucleases that show specificity for double-stranded RNA (dsRNA). RNase III is conserved in all known bacteria and eukaryotes and has 1-2 copies of a 9-residue consensus sequence, known as the RNase III signature motif. The bacterial RNase III proteins are the simplest, consisting...
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