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Stable and highly fluorescent small semiconducting polymer dots (Pdots) are prepared by D. T. Chiu and co‐workers using a covalent cross‐linking strategy described on page 3498. In this confocal fluorescence microscopy image, microtubules in HeLa cells are specifically labeled by the cross‐linked Pdots, and individual tubular structures can be seen under 488 nm laser illumination. Cross‐linked Pdots...
A facile cross‐linking strategy covalently links functional molecules to semiconducting polymer dots (Pdots) while simultaneously providing functional groups for biomolecular conjugation. In addition to greatly enhanced stability, the formed Pdots are small (<10 nm), which can be difficult to achieve with current methods but is highly desirable for most biological applications. These characteristics...
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