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Muscle pain and deep hyperalgesia are symptoms associated with a wide variety of painful syndromes. Electrophysiologic studies of the response properties of primary afferent fibers supplying skeletal muscle, as well as psychophysical measures of muscle pain sensation, have provided important information on the peripheral neural mechanisms underlying muscle pain sensation. It is believed that muscle...
The technique of intraneural microstimulation (INMS) combined with microneurography was used to excite and to record impulse activity in identified afferent peroneal nerve fibers from skeletal muscle of human volunteers. Microelectrode position was minutely adjusted within the impaled nerve fascicle until a reproducible sensation of deep pain projected to the limb was obtained during INMS. During...
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