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AimTargeting protein for Xenopus kinesin‐like protein 2 (TPX2) is a microtubule‐associated protein that impacts spindle assembly in human cells. Several studies have shown that the overexpression of TPX2 is correlated with multiple tumor types. However, the role of TPX2 in hepatocellular carcinoma (HCC) remains undetermined.
MethodsTPX2 expression was detected by quantitative reverse transcription...
Aim: F‐box and WD repeat domain‐containing 7 (Fbxw7) is a cell cycle regulatory gene that targets for ubiquitination and proteasomal degradation various cell cycle regulators such as c‐Myc and cyclin E. Defects in the Fbxw7 gene that lead to cell cycle re‐entry and expedite the G1‐S transition is thought to be one of the causes of cancer development. However, its expression and clinical importance...
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