Search results for: Małgorzata Kucińska

Items from 1 to 20 out of 21 results

article

Zagospodarowanie Górek Szymona

Małgorzata Kucińska

Przegląd Komunalny > 2022 > nr 2 > 79--81

Piaseczno to doskonały przykład, jak można pogodzić intensywny rozwój urbanistyczny z usługami ekosystemowymi.

article

The role of oxidative stress in 63 T-induced cytotoxicity against human lung cancer and normal lung fibroblast cell lines

Malgorzata Kucinska, Helena Mieszczak, Hanna Piotrowska-Kempisty, Mariusz Kaczmarek, more

Investigational New Drugs > 2019 > 37 > 5 > 849-864

Summary It has been shown previously that molecules built on benzanilide and thiobenzanilide scaffolds possess differential biological properties including selective anticancer activity. In our previous study, we examined the cytotoxic activity and mechanism of action of the thiobenzanilide derivative N,N′-(1,2-phenylene)bis3,4,5–trifluorobenzothioamide (63 T) as a potential chemotherapeutic compound...

article

EPR Oximetry Sensor—Developing a TAM Derivative for In Vivo Studies

Agnieszka Boś-Liedke, Magdalena Walawender, Anna Woźniak, Dorota Flak, more

Cell Biochemistry and Biophysics > 2018 > 76 > 1-2 > 19-28

Oxygenation is one of the most important physiological parameters of biological systems. Low oxygen concentration (hypoxia) is associated with various pathophysiological processes in different organs. Hypoxia is of special importance in tumor therapy, causing poor response to treatment. Triaryl methyl (TAM) derivative radicals are commonly used in electron paramagnetic resonance (EPR) as sensors for...

article

Antimicrobial and anticancer photodynamic activity of a phthalocyanine photosensitizer with N-methyl morpholiniumethoxy substituents in non-peripheral positions

Jolanta Dlugaszewska, Wojciech Szczolko, Tomasz Koczorowski, Paulina Skupin-Mrugalska, more

Journal of Inorganic Biochemistry > 2017 > 172 > C > 67-79

Photodynamic therapy involves the use of a photosensitizer that is irradiated with visible light in the presence of oxygen, resulting in the formation of reactive oxygen species. A novel phthalocyanine derivative, the quaternary iodide salt of magnesium(II) phthalocyanine with N-methyl morpholiniumethoxy substituents, was synthesized, and characterized. The techniques used included mass spectrometry...

article

Beyond mouse cancer models: Three-dimensional human-relevant in vitro and non-mammalian in vivo models for photodynamic therapy

Malgorzata Kucinska, Marek Murias, Patrycja Nowak-Sliwinska

Mutation Research/Reviews in Mutation Research > 2017 > 773 > C > 242-262

The proper design of experiments is a critical step for each study in order to obtain reproducible and reliable data. Taking into account constant competitiveness in the quickly developing biomedical sciences and the availability of sophisticated techniques, the choice and establishment of an experimental model system are essential for a successful research project. Currently, various sophisticated...

article

The protective activity of mesothelial cells against peritoneal growth of gastrointestinal tumors: The role of soluble ICAM-1

Justyna Mikuła-Pietrasik, Paweł Uruski, Małgorzata Kucińska, Andrzej Tykarski, more

The International Journal of Biochemistry & Cell Biology > 2017 > 86 > C > 26-31

In this project we examined how the presence of human peritoneal mesothelial cells (HPMCs) modifies (supports or inhibits) colorectal and pancreatic cancer cell progression in mice peritoneal cavity. Experiments were performed using primary, omentum-derived HPMCs, commercially available colorectal (SW-480) and pancreatic (PSN-1) cancer cells, and immunocompromised SCID mice. Tumor growth within the...

article

Role of CYP1A1 in the biological activity of methylated resveratrol analogue, 3,4,5,4′-tetramethoxystilbene (DMU-212) in ovarian cancer A-2780 and non-cancerous HOSE cells

Hanna Piotrowska-Kempisty, Agnieszka Klupczyńska, Dorota Trzybulska, Katarzyna Kulcenty, more

Toxicology Letters > 2017 > 267 > C > 59-66

The role of CYP1A1 and CYP1B1 enzymes in the biotransformation and biological activity of the methylated resveratrol analogue, 3,4,5,4′-tetramethoxystilbene (DMU-212) is still elusive. Our recently published data have shown that one of the metabolites of DMU-212, 3′-hydroxy-3,4,5,4′-tetramethoxystilbene (DMU-214) exerts more potent cytotoxic effects in A-2780 ovarian cancer cell line, as compared...

article

Selective anticancer activity of the novel thiobenzanilide 63T against human lung adenocarcinoma cells

Malgorzata Kucinska, Hanna Piotrowska-Kempisty, Natalia Lisiak, Mariusz Kaczmarek, more

Toxicology in Vitro > 2016 > 37 > C > 148-161

Previously, it has been reported that molecules built on the benzanilide and thiobenzanilide scaffold are the promising groups of compounds with several biological activities including antifungal, antimycotic, antibacterial, spasmolytic, and anticancer ones. In this study the mechanism of action of one selected thiobenzanilide derivative N,N′-(1,2-phenylene)bis3,4,5–trifluorobenzothioamide (63T) with...

article

Core–shell fluorinated methacrylate nanoparticles with Rhodamine-B for confocal microscopy and fluorescence correlation spectroscopy applications

Maciej Jarzebski, Yingze Zhang, Tomasz Sliwa, Jarosław Mazuryk, more

Journal of Fluorine Chemistry > 2016 > 183 > C > 92-99

There is a need to develop nanosized and submicron sized stable and efficient fluorescent particles for confocal microscopy and fluorescence correlation spectroscopy, which are useful methods to study dynamics and interactions in complex colloidal systems and living cells. Fluorescent core–transparent shell fluorinated polymer nanoparticles exhibit low refractive index, close to that of water, high...

article

Wyzwania dla samorządu województwa mazowieckiego wynikające ze zmian demograficznych w regionie

Zbigniew Strzelecki, Małgorzata Kucińska

Studia Ekonomiczne > 2016 > 290 > 158-172

Artykuł prezentuje wybrane zagadnienia dotyczące zmian demograficznych w województwie mazowieckim. Sytuacja demograficzna Mazowsza jest powiązana z polaryzacją jego rozwoju powodującą zróżnicowania przestrzenne problemów społecznych. Dlatego w pierwszej części artykułu zaprezentowano podstawowe cechy rozwoju społeczno-gospodarczego województwa mazowieckiego oraz wskazano główne trendy w rozwoju demograficznym...

article

Triterpenoid saponins and C-glycosyl flavones from stem bark of Erythrina abyssinica Lam and their cytotoxic effects.

Andy J. Pérez, Emad M. Hassan, Łukasz Pecio, Elsayed A. Omer, more

Phytochemistry Letters > 2015 > 13 > Complete > 59-67

Six new compounds including two oleanane-type triterpenoid saponins (1, 2) and four C-glycosyl flavones (3–6), along with a known saponin (7), three di-C-glycosyl flavones (8–10) and a glycosyl auronol (11), were isolated from the stem bark of Erythrina abyssinica Lam. The structures of the new compounds, identified as 3-O-[α-l-rhamnopyranosyl-(1→2)-β-d-galactopyranosyl-(1→2)-β-d-glucuronopyranosyl]-22-O-β-d-glucopyranosyl...

article

Characterization of new eye drops with choline salicylate and assessment of their irritancy by in vitro short time exposure tests

Katarzyna Wroblewska, Małgorzata Kucinska, Marek Murias, Janina Lulek

Saudi Pharmaceutical Journal > 2015 > 23 > 4 > 407-412

The aim of our study was to examine the irritation potential of new eye drops containing 2% choline salicylate (CS) as an active pharmaceutical ingredient (API) and various polymers increasing eye drop viscosity (hydroxyethylcellulose, hydroxypropyl methylcellulose, methylcellulose, polyvinyl alcohol, polyvinylpyrrolidone). The standard method for assessing the potential of irritating substances has...

article

Contribution of Research Project to the Evidence-Based Development Policies – an Example of the Development Trends of Mazovian Region Project

Zbigniew Strzelecki, Małgorzata Kucińska, Mirosław Grochowski, Tomasz Zegar

MAZOWSZE Studia Regionalne > 2015 > 17 > 115-137

Evidence-based policies require data and information on determinants, trends, and consequences of ongoing development processes. This data and information must be conveyed to policy makers. Thus a mechanism is needed to reach them and equip them with arguments for or against specific policy options. This mechanism is to be incorporated into the system of monitoring, analyzing, planning, and managing...

article

Photophysical properties and photochemistry of a sulfanyl porphyrazine bearing isophthaloxybutyl substituents

Sebastian Lijewski, Mateusz Gierszewski, Lukasz Sobotta, Jaroslaw Piskorz, more

Dyes and Pigments > 2015 > 113 > Complete > 702-708

A magnesium porphyrazine possessing isophthaloxybutylsulfanyl substituents in the periphery was synthesized and subjected to various photophysical studies, including optical absorption and emission measurements. Moreover, synchronous fluorescence spectra were recorded and a contour three-dimensional map of the excitation-emission of the studied porphyrazine was obtained. The porphyrazine macrocycle...

article

Nazwiska mieszkańców dawnych powiatów mławskiego i szreńskiego równe nazwom zawodów (1660–1825)*

Małgorzata Kucińska

Prace Językoznawcze > 2015 > 17/1 > 33-40

In the analyzed material, there are 110 surnames dependent on professions and performed functions. Anthroponyms dependent on the names of professions were characteristic mostly among the bourgeoisie, but there are also profession dependent surnames typical of villagers. Two types of anthroponyms have been distinguished: Polish (or acquired in the Polish language) and Latin. Profession-dependent surnames...

article

Prooxidative potential of hydroxylated resveratrol analogs

Malgorzata Kucinska, Hanna Piotrowska, Michał W. Luczak, Justyna Mikula-Pietrasik, more

Chemico-Biological Interactions > 2014 > 209 > Complete > 96-110

Resveratrol and its higher hydroxylated analogs have been reported to possess a variety of biological properties including antioxidant as well as prooxidant effects. The antioxidant properties are assumed to enable these compounds to protect cells from oxidative damage, however prooxidant activity are held likely to be responsible for their cytotoxic or pro-apoptotic effects. In present study the...

article

Imiennictwo w księgach chrztów dwóch mazowieckich parafii (Strzegowo i Wrona) na przełomie XVIII i XIX wieku

Małgorzata Kucińska

Prace Językoznawcze > 2014 > 16/1 > 87-95

The aim of the article is to present two most commonly given masculine and feminine names in two parishes of the northern Masovia at the end of the 18th and the beginning of the 19th century. Christian names prevailed in the material. Also, it can be assumed that the magical and protective functions were taken into consideration when choosing a name. The names were often given according to a calendar...

article

Synthesis, characterization, photochemical properties and cytotoxicity of the novel porphyrazine functionalized with nitroimidazolylbutylsulfanyl groups

Sebastian Lijewski, Jaroslaw Piskorz, Malgorzata Kucinska, Marcin Wierzchowski, more

Inorganic Chemistry Communications > 2013 > 29 > Complete > 97-100

A novel porphyrazine analog possessing nitroimidazolylbutylsulfanyl groups was synthesized and characterized using UV–Vis, IR, MS MALDI and various NMR techniques. In addition, a computational model following the Density Functional Theory method (DFT) was applied to analyze the FT IR spectrum. Potential photosensitizing activity of the novel porphyrazine was evaluated by measuring its ability to generate...

article

Expression of CYP1A1, CYP1B1 and MnSOD in a panel of human cancer cell lines

Hanna Piotrowska, Malgorzata Kucinska, Marek Murias

Molecular and Cellular Biochemistry > 2013 > 383 > 1-2 > 95-102

The expression of P450 enzymes and antioxidative enzymes in tumour tissue can have a major impact on the responsiveness of tumours to cancer chemotherapeutic drugs, therefore such information may be very precious when experiments are designed. The compressive information, concerning the expression of drug metabolism enzymes or antioxidative enzymes is still lacking, therefore in this study the expression...

article

Biological activity of piceatannol: Leaving the shadow of resveratrol

Hanna Piotrowska, Malgorzata Kucinska, Marek Murias

Mutation Research-Reviews in Mutation Research > 2012 > 750 > 1 > 60-82

Resveratrol (3,4′,5-trans-trihydroxystilbene), a naturally occurring stilbene, is considered to have a number of beneficial effects, including anticancer, anti-aethrogenic, anti-oxidative, anti-inflammatory, anti-microbial and estrogenic activity. Piceatannol (3,3′,4,5′-trans-trihydroxystilbene), a naturally occurring hydroxylated analogue of resveratrol, is less studied than resveratrol but displays...

Publication date

Last 3 years (1)

Close

Date range setting

Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.

From:

To:
Set your own date range

INFONA - science communication portal

Search results for: Małgorzata Kucińska

Zagospodarowanie Górek Szymona

The role of oxidative stress in 63 T-induced cytotoxicity against human lung cancer and normal lung fibroblast cell lines

EPR Oximetry Sensor—Developing a TAM Derivative for In Vivo Studies

Antimicrobial and anticancer photodynamic activity of a phthalocyanine photosensitizer with N-methyl morpholiniumethoxy substituents in non-peripheral positions

Beyond mouse cancer models: Three-dimensional human-relevant in vitro and non-mammalian in vivo models for photodynamic therapy

The protective activity of mesothelial cells against peritoneal growth of gastrointestinal tumors: The role of soluble ICAM-1

Role of CYP1A1 in the biological activity of methylated resveratrol analogue, 3,4,5,4′-tetramethoxystilbene (DMU-212) in ovarian cancer A-2780 and non-cancerous HOSE cells

Selective anticancer activity of the novel thiobenzanilide 63T against human lung adenocarcinoma cells

Core–shell fluorinated methacrylate nanoparticles with Rhodamine-B for confocal microscopy and fluorescence correlation spectroscopy applications

Wyzwania dla samorządu województwa mazowieckiego wynikające ze zmian demograficznych w regionie

Triterpenoid saponins and C-glycosyl flavones from stem bark of Erythrina abyssinica Lam and their cytotoxic effects.

Characterization of new eye drops with choline salicylate and assessment of their irritancy by in vitro short time exposure tests

Contribution of Research Project to the Evidence-Based Development Policies – an Example of the Development Trends of Mazovian Region Project

Photophysical properties and photochemistry of a sulfanyl porphyrazine bearing isophthaloxybutyl substituents

Nazwiska mieszkańców dawnych powiatów mławskiego i szreńskiego równe nazwom zawodów (1660–1825)*

Prooxidative potential of hydroxylated resveratrol analogs

Imiennictwo w księgach chrztów dwóch mazowieckich parafii (Strzegowo i Wrona) na przełomie XVIII i XIX wieku

Synthesis, characterization, photochemical properties and cytotoxicity of the novel porphyrazine functionalized with nitroimidazolylbutylsulfanyl groups

Expression of CYP1A1, CYP1B1 and MnSOD in a panel of human cancer cell lines

Biological activity of piceatannol: Leaving the shadow of resveratrol

Filter options

Publication date

Content availability

Publication language

Keywords

Data set

Journal

INFONA - science communication portal

Search results for: Małgorzata Kucińska

Add recipient

Sending message cancelled

Are you sure you want to cancel sending this message?

Send message

Filter options

Publication date

Date range setting

Set the date range to filter the displayed results. You can set a starting date, ending date or both. You can enter the dates manually or choose them from the calendar.

Content availability

Publication language

Keywords

Data set

Journal

Reporting an error / abuse

Sending the report failed

Accessibility options