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The renal papillary toxin, propyleneimine (PI), was administered at 20 or 30 μl/kg i.p. to male Sprague Dawley (SD) rats (n = 5), Fischer 344 (F344) rats (n = 4), and to multimammate desert mice (Mastomys natalensis, n = 4). Urine was collected at time points up to 4 days p.d. and the toxicological response of the different animal models to PI compared using 1 H NMR spectroscopy of urine,...
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