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Animal studies suggest that cannabinoid CB1 receptors play a role in regulating blood pressure (BP). In human studies, activation of CB1 receptors by cannabis or its active ingredient, Δ9-tetrahydrocannabinol (THC), has modest and inconsistent effects on BP.We evaluated this phenomenon in 63 male cannabis smokers (mean [SD] age 27.7 ± 5.4 years, 70% African American, 10.3 ± 5.9 years of lifetime cannabis...
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