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Theaflavin (TF) in black tea has been shown to have significant antioxidant and anti‐inflammatory capacity; however, the effects and the underlying mechanism of TF on atherosclerosis (AS) remain unclear. Herein, we investigated the effects and the potential mechanism of TF on AS progression in vivo and in vitro. ApoE−/− mice were administrated with high fat diet (HFD) or HFD + TF (5 or 10 mg, i.g...
Background Alternative polyadenylation (APA) has emerged as a pervasive mechanism that contributes to the transcriptome complexity and dynamics of gene regulation. The current tsunami of whole genome poly(A) site data from various conditions generated by 3′ end sequencing provides a valuable data source for the study of APA-related gene expression. Cluster analysis is a powerful technique for investigating...
Network intrusion detection based on SVM is the hot topic of network security research, and the existing researches have low detection rate, high false positive rate and other issues. Optimizing particle swarm optimization parameters of SVM is an effective solution, but the PSO algorithm is easy to fall into local optimum and results premature convergence.We propose an improved particle swarm optimization...
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