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Paclitaxel (PTX) is an effective chemotherapeutic agent for cancer patients. It has been reported that circular RNA (circRNA) circ_0005785is involved in the progression of hepatocellular carcinoma (HCC). The purpose of this study is to explore the role and mechanism of circ_0005785 in the PTX resistance of HCC. Cell viability, proliferation, invasion, migration, apoptosis, and angiogenesis were detected...
Polygonal wear seriously decreases the lifespan of a tire of a passenger car and adversely affects vehicle dynamic safety. The present paper builds a model that reflects the dynamic contact characteristics of the tire and reveals the mechanism and conditions of polygonal wear of a tire. The model describes the dynamic contact behavior of the tread block and considers the characteristics of dynamic...
Simplifying the tread-road model, a finite element model of the tire tread lateral self-excited vibration using LuGre friction model is established in MSC.Marc. With the finite element model, the lateral self-excited vibration of tread is simulated and analysed. Spectral analysis of the vibration signal is carrid out as well. At last, the influence of vehicle speed on lateral self-excited vibration...
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