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The application of manganese-enhanced MRI (MEMRI) to measure retinal function in humans is unclear. To begin to address this gap, we tested the hypothesis that an FDA-approved manganese-based MRI contrast agent, Teslascan, is useful for measuring functional intraretinal ionic regulation.Anesthetized dark- or light-adapted male healthy Sprague–Dawley rats were infused for 30min with 10μmol/kg of Teslascan...
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