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We evaluated longitudinal effects of alendronate on MRI-based trabecular bone structure parameters derived from dual thresholding and fuzzy clustering (BE-FCM) trabecular bone segmentation. Treatment effects were observed in the distal tibia after 24months. The BE-FCM method increased correlations to HR-pQCT-based parameters.High-resolution magnetic resonance imaging (MRI) allows for non-invasive...
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