Using the macaque model of androgenetic alopecia, we examined the effects of RU58841 on hair growth in the frontal bald scalp, and the rate of follicular cyclic growth was analyzed by micromorphometry (folliculogram) in biopsied skin. Solutions of RU58841, 5, 3, 1, and 0.5%, and vehicle (propylene glycol, isopropranol, isopropyl myristate, water, 50:30:2;18%) were applied topically, once per day,...
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