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We investigated the roles of the non-coding transcripts and found that expression of a fragment containing the 3′-untranslated region (3′-UTR) of nephronectin in osteoblast progenitor cells MC3T3-E1 promoted cell differentiation dramatically. We hypothesized that the ectopically expressed 3′-UTR binds microRNAs and modulates their functions. β-Catenin and GSK3β were up-regulated in the 3′-UTR-transfected...
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