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Microfabricated elastomeric scaffolds with 3D structural patterns are created by semiautomated layer‐by‐layer assembly of planar polymer sheets with through‐pores. The mesoscale interconnected pore architectures governed by the relative alignment of layers are shown to direct cell and muscle‐like fiber orientation in both skeletal and cardiac muscle, enabling scale up of tissue constructs towards...
Microfabricated biodegradable scaffolds with 3D structural patterns are created by semi‐automated layer‐by‐layer assembly of elastomeric polymer sheets with through‐pores, as described by Lisa E. Freed and co‐workers on page 4459. The 3D pore network architecture defined by the relative alignment of layers directed cell and muscle‐like fiber orientation in skeletal and cardiac muscle. In this picture,...
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