Search results for: Xiurong Yang

Items from 1 to 20 out of 179 results

article

Encapsulation of Enzymes into Hydrophilic and Biocompatible Metal Azolate Framework: Improved Functions of Biocatalyst in Cascade Reactions and its Sensing Applications

Qilin Zhao, Donghui Wu, Yu Wang, Tian Meng, more

Small > 20 > 31 > n/a - n/a

Multiple enzyme‐triggered cascade biocatalytic reactions are vital in vivo or vitro, considering the basic biofunction preservation in living organisms and signals transduction for biosensing platforms. Encapsulation of such enzymes into carrier endows a sheltering effect and can boost catalytic performance, although the selection and preparation of an appropriate carrier is still a concern. Herein,...

article

Enhanced Detection of Novel Low‐Frequency Gene Fusions via High‐Yield Ligation and Multiplexed Enrichment Sequencing

Yi Wu, Jinxiao Guo, Wenjun Li, Xuehao Xiu, more

Angewandte Chemie International Edition > 63 > 18 > n/a - n/a

Panel‐based methods are commonly employed for the analysis of novel gene fusions in precision diagnostics and new drug development in cancer. However, these methods are constrained by limitations in ligation yield and the enrichment of novel gene fusions with low variant allele frequencies. In this study, we conducted a pioneering investigation into the stability of double‐stranded adapter DNA, resulting...

article

Enhanced Detection of Novel Low‐Frequency Gene Fusions via High‐Yield Ligation and Multiplexed Enrichment Sequencing

Yi Wu, Jinxiao Guo, Wenjun Li, Xuehao Xiu, more

Angewandte Chemie > 136 > 18 > n/a - n/a

article

Programmable Atom‐Like Nanoparticle Reporters for High‐Precision Urinalysis of In Situ Membrane Proteins

Fei Ding, Shuangye Zhang, Qian Chen, Xiaodong Xie, more

Advanced Materials > 36 > 11 > n/a - n/a

The expression of disease‐specific membrane proteins (MPs) is a crucial indicator for evaluating the onset and progression of diseases. Urinalysis of in situ MPs has the potential for point‐of‐care disease diagnostics, yet remains challenging due to the lack of molecular reporter to transform the expression information of in situ MPs into the measurable urine composition. Herein, a series of tetrahedral...

article

Contrary Logic Pair Library, Parity Generator/Checker and Various Concatenated Logic Circuits Engineered by a Label‐Free and Immobilization‐Free Electrochemiluminescence Resonance Energy Transfer System

Liping Zhu, Linying Yu, Tian Meng, Yao Peng, more

Small > 17 > 46 > n/a - n/a

Herein, a label‐free and immobilization‐free electrochemiluminescence resonance energy transfer (ECL‐RET) system based on graphitic carbon nitride nanosheets (GCNNs)/Ru(phen)₃²⁺ donor/acceptor pair is developed, in which the ECL‐RET is regulated by regulating the diffusivity of Ru(phen)₃²⁺ molecules toward the negatively charged GCNNs through logically programmed DNA hybridization reactions. The two...

article

Rational Construction of Ruthenium‐Cobalt Oxides Heterostructure in ZIFs‐Derived Double‐Shelled Hollow Polyhedrons for Efficient Hydrogen Evolution Reaction

Libing Fan, Tian Meng, Mengxia Yan, Dewen Wang, more

Small > 17 > 26 > n/a - n/a

Transition metal oxides (TMOs) and their heterostructure hybrids have emerged as promising candidates for hydrogen evolution reaction (HER) electrocatalysts based on the recent technological breakthroughs and significant advances. Herein, Ru‐Co oxides/Co₃O₄ double‐shelled hollow polyhedrons (RCO/Co₃O₄‐350 DSHPs) with Ru‐Co oxides as an outer shell and Co₃O₄ as an inner shell by pyrolysis of core‐shelled...

article

Identifying the Activation Mechanism and Boosting Electrocatalytic Activity of Layered Perovskite Ruthenate

Qun Li, Dewen Wang, Qingqing Lu, Tian Meng, more

Small > 16 > 7 > n/a - n/a

SrRuO₃ as a rare conductive perovskite ruthenate has attracted increasing attention for application in energy conversion. Here, the electrocatalytic activity for the hydrogen evolution reaction (HER) of thermally synthesized layered SrRuO₃ is investigated and shows a considerable activation during cathodic polarization in alkaline solution. The analysis demonstrates the electrode activation is caused...

article

Isolation, characterization, and SREBP1 functional analysis of mammary epithelial cell in buffalo

Wenwen Xu, Qiuming Chen, Yinhai Jia, Jixian Deng, more

Journal of Food Biochemistry > 43 > 11 > n/a - n/a

Compared to cow milk, buffalo milk contains more protein, fat, and vitamin. Buffalo milk is an ideal food in human life. Sterol regulatory element‐binding protein 1 (SREBP1), an important transcription factor, regulates the expression and activity of enzyme and protein involved in milk fat synthesis to influence on the synthesis and secretion of triglyceride in mammary epithelial cells. In the present...

article

Cryosurvival and pregnancy rates: One‐step protocol for freezing–thawing Shangri‐la Yak (Bos grunniens) Embryos

Yinhai Jia, Xiurong Yang, Chengfu Zhang, Shangzhi Yang, more

Reproduction in Domestic Animals > 53 > 5 > 1168 - 1175

The yak is one of the most important and economically useful animals for highlanders. The decline in the yak population requires effective measures for the conservation and multiplication of elite germplasm. A standardized protocol will simplify the freezing and warming of yak embryos in straw and facilitate embryo transfer. In this work, we investigated a one‐step protocol that uses a stable basal...

article

One-pot synthesis of interconnected Pt₉₅Co₅ nanowires with enhanced electrocatalytic performance for methanol oxidation reaction

Qingqing Lu, Litai Sun, Xue Zhao, Jianshe Huang, more

Nano Research > 2018 > 11 > 5 > 2562-2572

Shape- and composition-controlled synthesis of platinum-based nanocrystals (NCs) is critical for the development of electrocatalysts that have high activity toward the methanol oxidation reaction (MOR) in direct methanol fuel cells (DMFCs). We report one-pot surfactant-free synthesis of interconnected Pt₉₅Co₅ nanowires (NWs) via an oriented attachment process, which has distinct advantages over conventional...

article

Cobalt Sulfide Nanowires Core Encapsulated by a N, S Codoped Graphitic Carbon Shell for Efficient Oxygen Reduction Reaction

Ce Han, Qun Li, Dewen Wang, Qingqing Lu, more

Small > 14 > 17 > n/a - n/a

Exploration of economical electrocatalysts for highly efficient and stable oxygen reduction reaction (ORR) is believed to be essential for diverse future renewable energy applications. Herein, cobalt sulfide nanowire core encapsulated in a N, S codoped graphitic carbon shell (CoS NWs@NSC) is successfully fabricated via the calcination of polydopamine‐coated Co(CO₃)_0.5(OH)_0.11H₂O NWs with sulfur powder...

article

Copper sulfide nanoplates as nanosensors for fast, sensitive and selective detection of DNA

Dewen Wang, Qun Li, Zhicai Xing, Xiurong Yang

Talanta > 2018 > 178 > C > 905-909

The present communication reports on a novel high-sensitivity DNA sensor based on cooper sulfide nanoplates (CuS NPs). The CuS NPs are successfully synthesized through a mild one-step hydrothermal method. As an efficient nanosensor for the fluorescent detection of DNA, the CuS NPs possess high sensitivity and selectivity with a detection limit of 25pM

article

FeS2-doped MoS2 nanoflower with the dominant 1T-MoS2 phase as an excellent electrocatalyst for high-performance hydrogen evolution

Xue Zhao, Xiao Ma, Qingqing Lu, Qun Li, more

Electrochimica Acta > 2017 > 249 > C > 72-78

Well-established methods to improve the hydrogen evolution reaction (HER) performances include, but are not limited to, tailoring the morphology and electronic structure of transition metal dichalcogenides (TMDs), and doping of earth abundant chemicals such as iron pyrite FeS₂ into existing TMDs. In this work, MoS₂ nanoflowers with the majority being octahedral MoS₂ (1T-MoS₂) and doped with FeS₂ were...

article

Label-free fluorescence turn-on strategy for trypsin activity based on thiolate-protected gold nanoclusters with bovine serum albumin as the substrate

Dan Zhao, Chuanxia Chen, Jiahui Zhao, Jian Sun, more

Sensors and Actuators B: Chemical > 2017 > 247 > C > 392-399

By using bovine serum albumin (BSA) as the enzyme substrate, we propose a label-free, convenient, reliable and highly sensitive fluorescence “turn-on” assay for trypsin activity and inhibitor screening by means of fluorescent gold nanoclusters capped with 11-mercaptoundecanoic acid (namely AuNCs@11-MUA) for the first time. The principle for the assay depends on the following features: (1) Cu²⁺-triggered...

article

Colorimetric sandwich immunosensor for Aβ(1-42) based on dual antibody-modified gold nanoparticles

Tao Hu, Shasha Lu, Chuanxia Chen, Jian Sun, more

Sensors and Actuators B: Chemical > 2017 > 243 > C > 792-799

Amyloid β-peptide (Aβ) is now considered as a key predictor for preclinical diagnosis of Alzheimer’s disease (AD), whose diagnosis is still hampered by the lack of early, sensitive, and convenient tools. Herein, we propose a colorimetric sandwich immunosensor for Aβ_(1-42) based on dual antibody-modified gold nanoparticles. Bare AuNPs are successfully coated with N-terminal antibody of Aβ_(1-42) (N-Ab...

article

Highly fluorescent nitrogen and sulfur co-doped graphene quantum dots for an inner filter effect-based cyanide sensor

Chuanxia Chen, Dan Zhao, Tao Hu, Jian Sun, more

Sensors and Actuators B: Chemical > 2017 > 241 > C > 779-788

In this work, nitrogen and sulfur co-doped graphene quantum dots (N,S-GQDs), exhibiting bright blue fluorescence with an excellent quantum yield of 67%, were facilely prepared by one-pot pyrolysis of citric acid (carbon source) and cysteine (N and S sources). Compared to conventional GQDs, the doping of nitrogen/sulfur had significantly altered and uniformed the surface state, and the as-obtained...

article

Facile synthesis and optical properties of zincblende and wurtzite Cu3ZnInSnSe6 nanocrystals

Dehui Li, Jian Sun, Xue Zhao, Xiao Ma, more

Journal of Alloys and Compounds > 2016 > 689 > C > 425-431

Controllable synthesis of semiconductor nanocrystals is an attractive issue yet still remains challenging. Here, we describe our efforts toward this direction by a simple colloidal method to engineer quinary Cu₃ZnInSnSe₆ (CZITSe) nanocrystals with different crystal phases and shapes. In this work, wurtzite and zincblende CZITSe nanocrystals with different morphology could be selectively synthesized...

article

Antibody modified-silver nanoparticles for colorimetric immuno sensing of Aβ(1–40/1–42) based on the interaction between β-amyloid and Cu2+

Tao Hu, Chuanxia Chen, Guangming Huang, Xiurong Yang

Sensors and Actuators B: Chemical > 2016 > 234 > C > 63-69

In this work, we initially establish a colorimetric immunosensor using antibody modified-silver nanoparticles (AgNPs) for the specific detection of Aβ_{(1–40/1–42)}, which is now can be viewed as a predictor for preclinical diagnosis of Alzheimer’s disease, based on the interaction between β-amyloid and Cu²⁺. We conjugated the AgNPs surface with C-terminal antibody of Aβ_{(1–40/1–42)} (Ab-AgNPs)_. In the...

article

Self-supported nickel nitride as an efficient high-performance three-dimensional cathode for the alkaline hydrogen evolution reaction

Zhicai Xing, Qun Li, Dewen Wang, Xiurong Yang, more

Electrochimica Acta > 2016 > 191 > C > 841-845

Transition metal nitrides (TMNs) attract a lot of attention due to their excellent catalytic activities for energy related applications, although TMN catalysts developed as HER catalysts in alkaline environment are limited. Herein, we report a very simple and straightforward method to fabricate self-supported nickel nitride film on nickel foam (Ni₃N/NF) via direct nitridation of NF under NH₃ atmosphere...

article

Gold nanoclusters–Cu2+ ensemble-based fluorescence turn-on and real-time assay for acetylcholinesterase activity and inhibitor screening

Jian Sun, Xiurong Yang

Biosensors and Bioelectronics > 2015 > 74 > C > 177-182

Based on the specific binding of Cu²⁺ ions to the 11-mercaptoundecanoic acid (11-MUA)-protected AuNCs with intense orange–red emission, we have proposed and constructed a novel fluorescent nanomaterials–metal ions ensemble at a nonfluorescence off-state. Subsequently, an AuNCs@11-MUA–Cu²⁺ ensemble-based fluorescent chemosensor, which is amenable to convenient, sensitive, selective, turn-on and real-time...

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CAPILLARY ELECTROPHORESIS (10)
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GOLD NANOPARTICLES (8)
SURFACE PLASMON RESONANCE (8)
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INFONA - science communication portal

Search results for: Xiurong Yang

Encapsulation of Enzymes into Hydrophilic and Biocompatible Metal Azolate Framework: Improved Functions of Biocatalyst in Cascade Reactions and its Sensing Applications

Enhanced Detection of Novel Low‐Frequency Gene Fusions via High‐Yield Ligation and Multiplexed Enrichment Sequencing

Enhanced Detection of Novel Low‐Frequency Gene Fusions via High‐Yield Ligation and Multiplexed Enrichment Sequencing

Programmable Atom‐Like Nanoparticle Reporters for High‐Precision Urinalysis of In Situ Membrane Proteins

Contrary Logic Pair Library, Parity Generator/Checker and Various Concatenated Logic Circuits Engineered by a Label‐Free and Immobilization‐Free Electrochemiluminescence Resonance Energy Transfer System

Rational Construction of Ruthenium‐Cobalt Oxides Heterostructure in ZIFs‐Derived Double‐Shelled Hollow Polyhedrons for Efficient Hydrogen Evolution Reaction

Identifying the Activation Mechanism and Boosting Electrocatalytic Activity of Layered Perovskite Ruthenate

Isolation, characterization, and SREBP1 functional analysis of mammary epithelial cell in buffalo

Cryosurvival and pregnancy rates: One‐step protocol for freezing–thawing Shangri‐la Yak (Bos grunniens) Embryos

One-pot synthesis of interconnected Pt₉₅Co₅ nanowires with enhanced electrocatalytic performance for methanol oxidation reaction

Cobalt Sulfide Nanowires Core Encapsulated by a N, S Codoped Graphitic Carbon Shell for Efficient Oxygen Reduction Reaction

Copper sulfide nanoplates as nanosensors for fast, sensitive and selective detection of DNA

FeS2-doped MoS2 nanoflower with the dominant 1T-MoS2 phase as an excellent electrocatalyst for high-performance hydrogen evolution

Label-free fluorescence turn-on strategy for trypsin activity based on thiolate-protected gold nanoclusters with bovine serum albumin as the substrate

Colorimetric sandwich immunosensor for Aβ(1-42) based on dual antibody-modified gold nanoparticles

Highly fluorescent nitrogen and sulfur co-doped graphene quantum dots for an inner filter effect-based cyanide sensor

Facile synthesis and optical properties of zincblende and wurtzite Cu3ZnInSnSe6 nanocrystals

Antibody modified-silver nanoparticles for colorimetric immuno sensing of Aβ(1–40/1–42) based on the interaction between β-amyloid and Cu2+

Self-supported nickel nitride as an efficient high-performance three-dimensional cathode for the alkaline hydrogen evolution reaction

Gold nanoclusters–Cu2+ ensemble-based fluorescence turn-on and real-time assay for acetylcholinesterase activity and inhibitor screening

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