Search results for: Gregory D. Smith

Items from 1 to 20 out of 62 results

article

Rapamycin improves social and stereotypic behavior abnormalities induced by pre‐mitotic neuronal subset specific Pten deletion

David A. Narvaiz, Suzanne O. Nolan, Gregory D. Smith, Andrew J. Holley, more

Genes, Brain and Behavior > 22 > 4 > n/a - n/a

The mechanistic target of rapamycin (mTOR) pathway is a signaling system integral to neural growth and migration. In both patients and rodent models, mutations to the phosphatase and tensin homolog gene (PTEN) on chromosome 10 results in hyperactivation of the mTOR pathway, as well as seizures, intellectual disabilities and autistic behaviors. Rapamycin, an inhibitor of mTOR, can reverse the epileptic...

article

Relating volatiles analysis by GC–MS to Oddy test performance for determining the suitability of museum construction materials

Michael J. Samide, Mary C. Liggett, Jericha Mill, Gregory D. Smith

Heritage Science > 2018 > 6 > 1 > 1-10

Conservators’ decisions regarding the suitability of museum construction materials for use in proximity to artworks still rely heavily on accelerated corrosion tests like the Oddy test despite widespread criticisms. These issues include inconveniently long wait times, sensitivity to only those pollutants capable of tarnishing metals, a general sense of unreliability, exaggerated environmental conditions,...

article

The properties of Moso bamboo heat-treated with silicon oil

Dali Cheng, Tao Li, Gregory D. Smith, Bin Xu, more

European Journal of Wood and Wood Products > 2018 > 76 > 4 > 1273-1278

Bamboo is very vulnerable to mold fungi, which greatly limits its applications. In this paper, moso bamboo was heat-treated with silicon oil at temperatures of 160, 175, and 190 °C for a duration of 2 h. The physical–mechanical properties and mold resistance were investigated. The chemical action of silicon oil within bamboo was analyzed by FTIR spectroscopy on bamboo samples before and after the...

article

Influence of environmental humidity and temperature on the creep behavior of sandwich panel

Zheng Chen, Ning Yan, James Deng, Kate E Semple, more

International Journal of Mechanical Sciences > 2017 > 134 > C > 216-223

By establishing a 3D moisture-displacement finite element (FE) model, the influence of constant and cycle humidity and varied temperature on the flexural creep of the sandwich panel containing Kraft honeycomb core and wood composite skins was studied. The related experimental and published data were used for determining the parameters of FE model such as material properties and diffusion values. The...

article

Micronised Egyptian blue pigment: A novel near-infrared luminescent fingerprint dusting powder

Benjamin Errington, Glen Lawson, Simon W. Lewis, Gregory D. Smith

Dyes and Pigments > 2016 > 132 > C > 310-315

In this paper we demonstrate that micronised Egyptian blue pigment can be used as a safe and simple material to visualise latent fingerprints on non-porous surfaces as near-infrared luminescent impressions. This allows the detection of latent fingerprints on highly patterned and reflective surfaces that have proven challenging with existing techniques.

article

Chemical analysis of dyes on an Uzbek ceremonial coat: Objective evidence for artifact dating and the chemistry of early synthetic dyes

Victor J. Chen, Gregory D. Smith, Amanda Holden, Niloo Paydar, more

Dyes and Pigments > 2016 > 131 > C > 320-332

A silk cross-stitched man's overcoat in traditional Uzbek style in the Indianapolis Museum of Art was thought to originate from late 1800s to early 1900s. To shed light on its history and associated textile dye chemistry, threads from the coat were subjected to dye analysis by LC-DAD-ESI-MS. Dyes identified include seventeen natural colorants from barberry, larkspur, madder and cochineal, and forty-two...

article

Population Density and Moment-based Approaches to Modeling Domain Calcium-mediated Inactivation of L-type Calcium Channels

Xiao Wang, Kiah Hardcastle, Seth H. Weinberg, Gregory D. Smith

Acta Biotheoretica > 2016 > 64 > 1 > 11-32

We present a population density and moment-based description of the stochastic dynamics of domain $${\text{Ca}}^{2+}$$ Ca 2 + -mediated inactivation of L-type $${\text{Ca}}^{2+}$$ Ca 2 + channels. Our approach accounts for the effect of heterogeneity of local $${\text{Ca}}^{2+}$$ Ca 2 + signals on whole cell $${\text{Ca}}^{2+}$$ Ca 2 + currents;...

article

Characterization of Haku Maki prints from the “Poem” series using light-based techniques

Lynn Chua, Claire Hoevel, Gregory D. Smith

Heritage Science > 2016 > 4 > 1 > 1-11

Four brightly colored calligraphic prints from the “Poem” series (1970/71) by Japanese artist Haku Maki (1924–2000) were examined using multiple light-based analytical techniques in an effort to address conservation concerns regarding these artworks. A distracting white haze on the surface of some of the prints was determined by light microscopy and infrared microanalysis to be fungal mycelium from...

article

Analysis and quantitation of volatile organic compounds emitted from plastics used in museum construction by evolved gas analysis–gas chromatography–mass spectrometry

Michael J. Samide, Gregory D. Smith

Journal of Chromatography A > 2015 > 1426 > Complete > 201-208

Construction materials used in museums for the display, storage, and transportation of artwork must be assessed for their tendency to emit harmful pollution that could potentially damage cultural treasures. Traditionally, a subjective metals corrosion test known as the Oddy test has been widely utilized in museums for this purpose. To augment the Oddy test, an instrumental sampling approach based...

article

Flax and Hemp fiber-reinforced particleboard

Solace Sam-Brew, Gregory D. Smith

Industrial Crops and Products > 2015 > 77 > C > 940-948

The objective of this study was to reinforce particleboard products with natural bast fibers which have high tensile strength and stiffness-to-weight ratios. Three-layered particleboards were manufactured from Wood, Hurd and Shive particle furnish and reinforced in the upper and lower face layers with aligned Flax and Hemp fiber mats. Control particleboard samples were manufactured from 100% Wood,...

article

Hydrofluoric acid pre-treatment of matte artists’ paints for binding medium analysis by Fourier transform infrared microspectroscopy

Gregory D. Smith, Kwame E. Newton, Lisa Altherr

Vibrational Spectroscopy > 2015 > 81 > Complete > 46-52

A rapid and safe method has been developed for preparing matte artists’ paint samples for binding medium analysis by Fourier transform infrared (FTIR) microspectroscopy. Hydrofluoric acid (HF) transforms many inorganic components of matte paints that commonly interfere with medium analysis, viz. carbonate and silicate fillers and pigments, into chemical species whose infrared absorptions are shifted...

article

Fracture mechanisms of wood/polyester laminates under quasi-static compression and shear loading

Shayesteh Haghdan, Gregory D. Smith

Composites Part A > 2015 > 74 > Complete > 114-122

There is increasing use of natural fiber/polymer composites as alternatives to traditional structural materials like concrete and metals and to the inorganic fibers like carbon. While the fracture mechanisms during crushing of synthetic fiber/polymer composites have been thoroughly studied, limited information is available on post-fracture investigation and identification of the dominant fracture...

article

Ca2+-activation kinetics modulate successive puff/spark amplitude, duration and inter-event-interval correlations in a Langevin model of stochastic Ca2+ release

Xiao Wang, Yan Hao, Seth H. Weinberg, Gregory D. Smith

Mathematical Biosciences > 2015 > 264 > Complete > 101-107

Through theoretical analysis of the statistics of stochastic calcium (Ca ²⁺ ) release (i.e., the amplitude, duration and inter-event interval of simulated Ca ²⁺ puffs and sparks), we show that a Langevin description of the collective gating of Ca ²⁺ channels may be a good approximation to the corresponding Markov chain model when the number of Ca ²⁺ channels per Ca...

article

The Influence of Ca2+ Buffers on Free [Ca2+] Fluctuations and the Effective Volume of Ca2+ Microdomains

Seth H. Weinberg, Gregory D. Smith

Biophysical Journal > 2014 > 106 > 12 > 2693-2709

Intracellular calcium (Ca²⁺) plays a significant role in many cell signaling pathways, some of which are localized to spatially restricted microdomains. Ca²⁺ binding proteins (Ca²⁺ buffers) play an important role in regulating Ca²⁺ concentration ([Ca²⁺]). Buffers typically slow [Ca²⁺] temporal dynamics and increase the effective volume of Ca²⁺ domains. Because fluctuations in [Ca²⁺] decrease in proportion...

article

Buffer- and Diffusion-Mediated Calcium Concentration Fluctuations Accelerate the Stochastic Dynamics of Calcium-Triggered Events

Seth H. Weinberg, Gregory D. Smith

Biophysical Journal > 2014 > 106 > 2 Supplement 1 > 115a

article

A Population Density and Moment-Based Approach to Modeling Domain Calcium-Mediated Inactivation of L-Type Calcium Channels

Xiao Wang, Kiah Hardcastle, Seth H. Weinberg, Gregory D. Smith

Biophysical Journal > 2014 > 106 > 2 Supplement 1 > 135a

article

Calcium Concentration Fluctuations and Subspace Volume Influence Calcium-Regulated Calcium Channel Gating and Subspace Dynamics

Seth H. Weinberg, Gregory D. Smith

Biophysical Journal > 2013 > 104 > 2 Supplement 1 > 367a

article

Analysis of Spark Versus Non-Spark Mediated SR Calcium Leak using a Langevin Description of Stochastic Calcium Release

Xiao Wang, Yan Hao, Seth H. Weinberg, Eric A. Sobie, more

Biophysical Journal > 2013 > 104 > 2 Supplement 1 > 438a

article

A Population Density Domain Model for Calcium-Inactivation of L-Type Calcium Channels

Kiah Hardcastle, Seth H. Weinberg, Gregory D. Smith

Biophysical Journal > 2013 > 104 > 2 Supplement 1 > 460a

article

Modeling vertical density profile formation for strand-based wood composites during hot pressing: Part 2. Experimental investigations and model validation

Cheng Zhou, Chunping Dai, Gregory D. Smith

Composites Part B > 2011 > 42 > 6 > 1357-1365

As a continuation of previous paper on modeling vertical density profile (VDP) formation for wood strand composites, this paper presents typical prediction results from the VDP model and describes the experimental investigations. By taking into account the non-uniform mat structure, the model can predict not only the overall panel VDP but also the localized VDP of a given area within the panel. Thus...

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INFONA - science communication portal

Search results for: Gregory D. Smith

Rapamycin improves social and stereotypic behavior abnormalities induced by pre‐mitotic neuronal subset specific Pten deletion

Relating volatiles analysis by GC–MS to Oddy test performance for determining the suitability of museum construction materials

The properties of Moso bamboo heat-treated with silicon oil

Influence of environmental humidity and temperature on the creep behavior of sandwich panel

Micronised Egyptian blue pigment: A novel near-infrared luminescent fingerprint dusting powder

Chemical analysis of dyes on an Uzbek ceremonial coat: Objective evidence for artifact dating and the chemistry of early synthetic dyes

Population Density and Moment-based Approaches to Modeling Domain Calcium-mediated Inactivation of L-type Calcium Channels

Characterization of Haku Maki prints from the “Poem” series using light-based techniques

Analysis and quantitation of volatile organic compounds emitted from plastics used in museum construction by evolved gas analysis–gas chromatography–mass spectrometry

Flax and Hemp fiber-reinforced particleboard

Hydrofluoric acid pre-treatment of matte artists’ paints for binding medium analysis by Fourier transform infrared microspectroscopy

Fracture mechanisms of wood/polyester laminates under quasi-static compression and shear loading

Ca2+-activation kinetics modulate successive puff/spark amplitude, duration and inter-event-interval correlations in a Langevin model of stochastic Ca2+ release

The Influence of Ca2+ Buffers on Free [Ca2+] Fluctuations and the Effective Volume of Ca2+ Microdomains

Buffer- and Diffusion-Mediated Calcium Concentration Fluctuations Accelerate the Stochastic Dynamics of Calcium-Triggered Events

A Population Density and Moment-Based Approach to Modeling Domain Calcium-Mediated Inactivation of L-Type Calcium Channels

Calcium Concentration Fluctuations and Subspace Volume Influence Calcium-Regulated Calcium Channel Gating and Subspace Dynamics

Analysis of Spark Versus Non-Spark Mediated SR Calcium Leak using a Langevin Description of Stochastic Calcium Release

A Population Density Domain Model for Calcium-Inactivation of L-Type Calcium Channels

Modeling vertical density profile formation for strand-based wood composites during hot pressing: Part 2. Experimental investigations and model validation

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