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Using fast‐scan cyclic voltammetry paired with pharmacology, the authors show that infralimbic catecholamine release following locus coeruleus stimulation is noradrenergic, but not dopaminergic, and not affected by acute ethanol. With previous work, these data suggest differential effects of ethanol on prefrontal norepinephrine and dopamine, a region important in addiction‐related pathways.
BackgroundRodent studies have demonstrated that adolescent social isolation results in many behavioral perturbations, including increases in anxiety‐like behaviors. Socially isolated (SI) rats have also been shown to self‐administer greater amounts ethanol (EtOH) in some, but not all, studies. Here, we tested whether juvenile social isolation increases EtOH drinking using an intermittent procedure...
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