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Cleistochlamys kirkii (Benth) Oliv. (Annonaceae) is a medicinal plant traditionally used in Mozambique to treat infectious diseases. The aim of this study was to find resistance modifiers in C. kirkii for Gram‐positive and Gram‐negative model bacterial strains. One of the most important resistance mechanisms in bacteria is the efflux pump‐related multidrug resistance. Therefore, polycarpol (1), three...
Cleistochlamys kirkii (Benth) Oliv., (Annonaceae) is a medicinal plant traditionally used in Mozambique to treat infectious diseases.To find antibacterial lead compounds from C. kirkii and provide scientific validation for its use in traditional medicine.Through bioassay-guided fractionation, nine compounds (1–9), with different scaffolds, were isolated from the methanol extract of C. kirkii whose...
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