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Purpose
Our goal is to develop an accurate, automated tool to characterize the optic nerve (ON) and cerebrospinal fluid (CSF) to better understand ON changes in disease.
Methods
Multi‐atlas segmentation is used to localize the ON and sheath on T2‐weighted MRI (0.6 mm3 resolution). A sum of Gaussian distributions is fit to coronal slice‐wise intensities to extract six descriptive parameters, and...