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Nasal polyps, according to many authors, generate as a result of chronic inflammation process with activation of cytokines, immunological reaction mediators that regulate proliferation, differentiation and cell apoptosis. Clarifying molecular mechanisms present in those disturbances may have diagnostic and prognostic value in evaluation of recurrence, dynamics and differentiation of nasal polyps as...
Transforming growth factor β (TGF-β) plays an important role in cells proliferation and differentiation as well as in local immunological response.An evaluation of genes expression profile for TGF-β1 and its receptors TGF-βRI, TGF-β RII and TGF-β βRIII as well as their potential role in the pathogenesis of nasal polyps in eosynophilic and neutrophilic polyps and in normal nasal mucosa.Material consisted...
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