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The guanine nucleotide exchange factor RIC‐8 is a conserved protein essential for the asymmetric division in the early embryogenesis in different organisms. The function of RIC‐8 in mammalian development is not characterized so far. In this study we map the expression of RIC‐8 during the early development of mouse. To elucidate the RIC‐8 function we used Ric‐8−/− mutant embryos. The Ric‐8−/− embryos...
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