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Objective
Observations of microbial dysbiosis in patients with rheumatoid arthritis (RA) have raised interest in studying microbial–mucosal interactions as a potential trigger of RA. Using the murine collagen‐induced arthritis (CIA) model, we undertook this study to test our hypothesis that microbiota modulate immune responses leading to autoimmune arthritis.
Methods
CIA was induced by immunization...
Molting is induced in decapod crustaceans via multiple leg autotomy (MLA) or eyestalk ablation (ESA). MLA removes five or more walking legs, which are regenerated and become functional appendages at ecdysis. ESA eliminates the primary source of molt-inhibiting hormone (MIH) and crustacean hyperglycemic hormone (CHH), which suppress the production of molting hormones (ecdysteroids) from the molting...
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