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RNA molecules have emerged as increasingly attractive biomaterials with important applications such as RNA interference (RNAi) for cancer treatment and mRNA vaccines against infectious diseases. However, it remains challenging to engineer RNA biomaterials with sophisticated functions such as non‐covalent light‐switching ability. Herein, light‐responsive RNA‐protein nanowires are engineered to have...
RNA aptamers bind specifically and selectively to various macromolecules, cell surfaces, and viruses and find broad applications as biosensors, diagnostics, and in therapeutic treatments and drug delivery. Currently, RNA aptamer production is via in vitro methods. Herein, a new E. coli‐based approach has been demonstrated for the rapid production of multimeric RNA aptamer transcripts that are protected...
Assembled protein particles, as emerging biomaterials, have broad applications ranging from vaccines and drug delivery to biocatalysis and particle tracking, but to date these require trial‐and‐error rational design experimentation and/or intensive computational methods to generate. Here, the authors describe an easy‐to‐implement engineering strategy to generate customized protein particles as multifunctional...
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