Search results for: Carolina Samuelsson

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article

Malignant hyperthermia safety – A nationwide survey of publicly funded Swedish healthcare

Anna Hellblom, William Pettersson Miller, Maria Soller, Carolina Samuelsson

Acta Anaesthesiologica Scandinavica > 68 > 6 > 788 - 793

Background Malignant hyperthermia (MH) is a rare pharmacogenetic disorder that can lead to a life‐threatening reaction during general anaesthesia with triggering agents. Prompt life‐saving treatment includes the immediate administration of the antidote dantrolene. This study investigated Swedish healthcare providers' awareness and adherence to guidelines and recommendations with respect to MH and...

article

Disturbance in the oropharyngeal microbiota in relation to antibiotic and proton pump inhibitor medication and length of hospital stay

Anna Tranberg, Carolina Samuelsson, Bengt Klarin

APMIS > 129 > 1 > 14 - 22

The aim of this study was to investigate the appearance of a disturbed oropharyngeal microbiota during hospitalization and explore the patient characteristics that maybe associated with such a disturbance. Oropharyngeal swabs were collected from 134 patients at hospital admission and every 3–4 days thereafter. The samples were cultivated to determine the presence of a disturbed microbiota, which,...

article

Preanesthetic nurse communication with children and parents—an observational study

Chris Perry, Carolina Samuelsson, Allan M. Cyna, Adrian Bosenberg

Pediatric Anesthesia > 25 > 12 > 1235 - 1240

BackgroundThe impact of communication within the perioperative period is an area of increasing research interest. Suggestions are phrases or actions that can lead to subconscious nonvolitional changes in patient perception, mood, and/or behavior. Statements functioning as suggestions may induce positive or negative perceptual responses and experiences. Children and anxious patients are particularly...

article

Gender differences in outcome and use of resources do exist in Swedish intensive care, but to no advantage for women of premenopausal age

Carolina Samuelsson, Folke Sjöberg, Göran Karlström, Thomas Nolin, more

Critical Care > 2015 > 19 > 1 > 1-9

Introduction Preclinical data indicate that oestrogen appears to play a beneficial role in the pathophysiology of and recovery from critical illness. In few previous epidemiologic studies, however, have researchers analysed premenopausal women as a separate group when addressing potential gender differences in critical care outcome. Our aim was to see if women of premenopausal age have a better...

article

Lactic acid bacteria colonization and clinical outcome after probiotic supplementation in conventionally treated bacterial vaginosis and vulvovaginal candidiasis

Sophia Ehrström, Katalin Daroczy, Eva Rylander, Carolina Samuelsson, more

Microbes and Infection > 2010 > 12 > 10 > 691-699

This randomized double-blind placebo controlled study assessed the vaginal colonization of lactic acid bacteria and clinical outcome. Vaginal capsules containing L gasseri LN40, Lactobacillus fermentum LN99, L. casei subsp. rhamnosus LN113 and P. acidilactici LN23, or placebos were administered for five days to 95 women after conventional treatment of bacterial vaginosis and/or vulvovaginal candidiasis...

article

Microdialysis patterns in subarachnoid hemorrhage patients with focus on ischemic events and brain interstitial glutamine levels

Carolina Samuelsson, Lars Hillered, Per Enblad, Elisabeth Ronne-Engström

Acta Neurochirurgica > 2009 > 151 > 5 > 437-446

Background This observational microdialysis (MD) study of 33 subarachnoid hemorrhage patients explores brain interstitial levels of glutamine, glutamate, lactate and pyruvate, and their relationship to clinical status and clinical course at the neurointensive care unit. Methods The focus was on ischemic events, defined by clinical criteria or by radiology, and the significance of brain interstitial...

article

Temporal patterns of interstitial pyruvate and amino acids after subarachnoid haemorrhage are related to the level of consciousness—a clinical microdialysis study

Maria Zetterling, Lars Hillered, Carolina Samuelsson, Torbjörn Karlsson, more

Acta Neurochirurgica > 2009 > 151 > 7 > 771-780

Background Temporal patterns of brain interstitial amino acids after subarachnoid haemorrhage (SAH) were studied in relation to energy metabolite levels and to the severity of the initial global ischaemia as reflected by the level of consciousness at admission. Method Intracerebral microdialysis was used to measure brain interstitial amino acids and the energy metabolites glucose, lactate, and pyruvate...

article

The effects of PBN (phenyl-butyl-nitrone) on GLT-1 levels and on the extracellular levels of amino acids and energy metabolites in a model of iron-induced posttraumatic epilepsy

Carolina Samuelsson, Eva Kumlien, Åse Elfving, Dan Lindholm, more

Epilepsy Research > 2003 > 56 > 2-3 > 165-173

This study investigates astrocytic glutamate uptake in the iron-induced animal model of posttraumatic epilepsy. Since formation of free radicals may be involved in epileptogenesis after brain trauma and hemorrhage the effects of the nitrone radical scavenger α-phenyl-tert-N-butyl nitrone (PBN) were also studied. Animals received an intracortical iron injection, or were sham-operated. They were given...

article

Decreased cortical levels of astrocytic glutamate transport protein GLT-1 in a rat model of posttraumatic epilepsy

Carolina Samuelsson, Eva Kumlien, Roland Flink, Dan Lindholm, more

Neuroscience Letters > 2000 > 289 > 3 > 185-188

The extracellular homeostasis of glutamate in the brain is maintained by the efficient uptake into astroglial cells. The high extracellular glutamate levels seen during seizures are therefore probably a result of both an increased synaptic release and a deranged glutamate uptake. In this study we used immuno-blotting technique to measure the cortical levels of the astrocytic glutamate transport protein...

article

Studies on the interaction between hyaluronan and a rat colon cancer cell line

Carolina Samuelsson, Stefan Gustafson

Glycoconjugate Journal > 1998 > 15 > 2 > 169-175

Binding studies with 125I-Tyr labelled hyaluronan (HA) on a cultured rat colon cancer cell line were performed to characterize the association of HA to tumour cells in vitro. Results show a specific and saturable binding (Kd= 1.36nM) which indicates the presence of an HA binding receptor on the tumour cells. There is a specific constant increase of cell-associated HA over time, which indicates that...

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Keywords

AMINO ACIDS (2)
GLUTAMATE (2)
IRON (2)
MICRODIALYSIS (2)
ANIMAL MODEL (1)
ANTIBIOTICS (1)
BACTERIAL VAGINOSIS (1)
BINDING (1)
CHILD (1)
COMMUNICATION (1)
DANTROLENE (1)
EPILEPSY (1)
GLT-1 (1)
GLUTAMATE AND ASPARTATE TRANSPORTING PROTEIN (1)
GLUTAMATE UPTAKE (1)
GLUTAMINE (1)
HOSPITALIZATION (1)
HYALURONIC ACID (1)
ISCHEMIA (1)
LACTATE/PYRUVATE RATIO (1)
LACTOBACILLI (1)
LANGUAGE (1)
MALIGNANT HYPERTHERMIA (1)
NITRONES (1)
NOSOCOMIAL INFECTION (1)
NURSING STAFF (1)
OROPHARYNGEAL MICROBIOTA (1)
PATIENT SAFETY (1)
POLYSACCHARIDES (1)
POSTTRAUMATIC EPILEPSY (1)
PPI (1)
PREOPERATIVE CARE (1)
PROBIOTICS (1)
PYRUVATE (1)
RAPD ANALYSIS (1)
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SCAVENGER RECEPTOR LIGANDS (1)
SUBARACHNOID HAEMORRHAGE (1)
SUBARACHNOID HEMORRHAGE (1)
SUGGESTION (1)
TRAUMATIC BRAIN INJURY (1)
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