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The fluorescence-based integrated chemical and enzyme sensor arrays on which two kinds of 10 μm i.d. sensor spots were arranged alternately on one chip, were developed by using microcontact printing. FITC, ruthenium complex and europium tetracycline was stamped onto a DLC sputtered glass slides for pH, oxygen and hydrogen peroxide sensors, respectively. After printing of oxygen sensor spots, pH sensor...
We performed single-molecule observation of DNA double-strand breaks caused by Co60 γ-ray irradiation and quantitatively evaluated the protective effect of ascorbic acid 2-glucoside (AA-2G). AA-2G is a stable derivative of ascorbic acid. We found that AA-2G induces a significant conformational change on DNA. We also evaluated the protective effect of AA-2G against radiation-induced DNA double-strand...
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