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Scar formation after wound repair affects people's daily life. Mesenchymal stem cells were reported to have a beneficial role in attenuating the scar formation. In the present study, placenta-derived mesenchymal stem cells (PMSCs) were isolated and the effects of hypoxic conditioned medium of PMSCs on scar formation were explored.To evaluate the effect of hypoxia on PMSCs, proliferation of PMSCs was...
Objectives To explore the effect of placenta-derived mesenchymal stem cells on scar formation as well as the underlying mechanism. Results The isolated placenta-derived mesenchymal stem cells from mice were distributed in the wounded areas of scalded mouse models, attenuated inflammatory responses and decreased the deposition of collagens, thus performing a beneficial effect against scar formation...
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