Search results for: Joseph G. Hentz

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article

Headache characteristics and burden from chronic migraine with medication overuse headache: Cross‐sectional observations from the Medication Overuse Treatment Strategy trial

Todd J. Schwedt, Joseph G. Hentz, Soma Sahai‐Srivastava, Nicole M. Spare, more

Headache: The Journal of Head and Face Pain > 61 > 2 > 351 - 362

Objective To describe headache characteristics, medication use, disability, and quality of life in a large patient cohort from the United States who have chronic migraine (CM) and medication overuse headache (MOH). Methods In all, 610 adult patients were enrolled into the Medication Overuse Treatment Strategy trial from 34 healthcare clinics, including headache specialty, general neurology, and...

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Lewy body pathology in Alzheimer's disease: A clinicopathological prospective study

Rodolfo Savica, Thomas G. Beach, Joseph G. Hentz, Marwan N. Sabbagh, more

Acta Neurologica Scandinavica > 139 > 1 > 76 - 81

Objective Identify clinical features predictive of Lewy body pathology in Alzheimer's disease (AD) patients in an ongoing longitudinal clinicopathologic study. Material and Methods We queried the Arizona Study of Aging and Neurodegenerative Disorders (AZSAND) database for dementia cases with AD pathology (1997‐2015). Subjects received longitudinal comprehensive clinical evaluations including motor/neuropsychological...

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Peripheral synucleinopathy in early Parkinson's disease: Submandibular gland needle biopsy findings

Charles H. Adler, Brittany N. Dugger, Joseph G. Hentz, Michael L. Hinni, more

Movement Disorders > 32 > 5 > 722 - 723

article

A resilience intervention involving mindfulness training for transplant patients and their caregivers

Cynthia M. Stonnington, Betty Darby, Angela Santucci, Pamela Mulligan, more

Clinical Transplantation > 30 > 11 > 1466 - 1472

Solid organ and stem cell transplant patients and their caregivers report a substantial level of distress. Mindfulness‐based stress reduction has been shown to alleviate distress associated with transplant, but there is limited experience in this population with other mindfulness‐based interventions, or with combined transplant patient and caregiver interventions. We evaluated a novel, 6‐week mindfulness‐based...

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Cortical phosphorylated α‐Synuclein levels correlate with brain wave spectra in Parkinson's disease

John N. Caviness, Lih‐Fen Lue, Joseph G. Hentz, Christopher T. Schmitz, more

Movement Disorders > 31 > 7 > 1012 - 1019

IntroductionQuantitative EEG features have been identified as surrogates and predictors of cognitive decline/dementia, a common feature of progressive PD. The biochemical correlates for altered quantitative EEG features are unknown. Our primary objective was to test the hypothesis that quantitative EEG measures correlate with cortical levels of phosphorylated α‐synuclein, a modified form of the synaptic...

article

Assessing medication role on neuropathological findings in Parkinson's disease

Charles H. Adler, Joseph G. Hentz, Thomas G. Beach

Movement Disorders > 31 > 5 > 613 - 614

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Graph theory network function in Parkinson’s disease assessed with electroencephalography

Rene L. Utianski, John N. Caviness, Elisabeth C.W. van Straaten, Thomas G. Beach, more

Clinical Neurophysiology > 2016 > 127 > 5 > 2228-2236

To determine what differences exist in graph theory network measures derived from electroencephalography (EEG), between Parkinson’s disease (PD) patients who are cognitively normal (PD-CN) and matched healthy controls; and between PD-CN and PD dementia (PD-D).EEG recordings were analyzed via graph theory network analysis to quantify changes in global efficiency and local integration. This included...

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Peripheral Synucleinopathy in Early Parkinson's Disease: Submandibular Gland Needle Biopsy Findings

Charles H. Adler, Brittany N. Dugger, Joseph G. Hentz, Michael L. Hinni, more

Movement Disorders > 31 > 2 > 250 - 256

IntroductionFinding a peripheral tissue biopsy site to diagnose early PD would be of value for clinical care, biomarker validation, and as research enrollment criteria. Whereas autopsy and advanced PD studies suggest that the submandibular gland is an important biopsy site, there are no studies in early PD. The aim of this study was to determine whether needle biopsy of the submandibular gland reveals...

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Simplified conversion method for unified Parkinson's disease rating scale motor examinations

Joseph G. Hentz, Shyamal H. Mehta, Holly A. Shill, Erika Driver‐Dunckley, more

Movement Disorders > 30 > 14 > 1967 - 1970

BackgroundWe evaluated a simplified method for converting Unified Parkinson's Disease Rating Scale Part III Motor Examination total scores (UPDRS III) to the International Parkinson and Movement Disorder Society's (MDS) revised version of the scores. MethodsPD patients in the Arizona Study of Aging and Neurodegenerative Disorders were assessed with both scales. The accuracy of the predicted scores...

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REM sleep behavior disorder and neuropathology in Parkinson's disease

Ronald B. Postuma, Charles H. Adler, Brittany N. Dugger, Joseph G. Hentz, more

Movement Disorders > 30 > 10 > 1413 - 1417

IntroductionRapid eye movement (REM) sleep behavior disorder (RBD) in Parkinson's disease (PD) is associated with differences in clinical phenotype, including dementia, autonomic loss, and gait dysfunction. The pathological basis for this remains unclear. MethodsParkinson's disease subjects in a longitudinal clinicopathologic study were screened for probable RBD with the Mayo Sleep Questionnaire...

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Arizona Study of Aging and Neurodegenerative Disorders and Brain and Body Donation Program

Thomas G. Beach, Charles H. Adler, Lucia I. Sue, Geidy Serrano, more

Neuropathology > 35 > 4 > 354 - 389

The Brain and Body Donation Program (BBDP) at Banner Sun Health Research Institute (http://www.brainandbodydonationprogram.org) started in 1987 with brain‐only donations and currently has banked more than 1600 brains. More than 430 whole‐body donations have been received since this service was commenced in 2005. The collective academic output of the BBDP is now described as the Arizona Study of Aging...

article

Quality of life in psychogenic nonepileptic seizures and epilepsy: The role of somatization and alexithymia

Laurie Dempsey Wolf, Joseph G. Hentz, Kristine S. Ziemba, Kristin A. Kirlin, more

Epilepsy & Behavior > 2015 > 43 > Complete > 81-88

It is clear that many individuals with psychogenic nonepileptic seizures (PNESs) often present with poorer quality of life compared with those with epileptic seizures (ESs). However, the mechanisms linking seizure diagnosis to quality-of-life outcomes are much less clear. Alexithymia and somatization are emotional markers of psychological functioning that may explain these differences in quality of...

article

The Chitranjan Ranawat Award: Periarticular Injections and Femoral & Sciatic Blocks Provide Similar Pain Relief After TKA: A Randomized Clinical Trial

Mark J. Spangehl, Henry D. Clarke, Joseph G. Hentz, Lopa Misra, more

Clinical Orthopaedics and Related Research® > 2015 > 473 > 1 > 45-53

Background Two of the more common methods of pain management after TKA are peripheral nerve blocks and intraarticular/periarticular injections. However, we are not aware of any study directly comparing the commonly used combination of a continuous femoral block given with a single-shot sciatic block with that of a periarticular injection after TKA. Questions/purposes This randomized clinical trial...

article

Neuropathological comparisons of amnestic and nonamnestic mild cognitive impairment

Brittany N. Dugger, Kathryn Davis, Michael Malek-Ahmadi, Joseph G. Hentz, more

BMC Neurology > 2015 > 15 > 1 > 1-8

Background Although there are studies investigating the pathologic origins of mild cognitive impairment (MCI), they have revolved around comparisons to normal elderly individuals or those with Alzheimer’s disease (AD) or other dementias. There are few studies directly comparing the comprehensive neuropathology of amnestic (aMCI) and nonamnestic (naMCI) MCI. Methods The database of the Brain and...

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The influence of staffing on diagnostic yield of EMU admissions: A comparison study between two institutions

Scott D. Spritzer, Benjamin D. Pirotte, Susan D. Agostini, Ejerzain Aniles, more

Epilepsy & Behavior > 2014 > 41 > C > 264-267

Patients with recurrent, stereotyped neurological events of unclear etiology often warrant admission for continuous video-EEG monitoring in an epilepsy monitoring unit (EMU) for diagnosis. Epilepsy monitoring unit admission duration has been reported to range from days to weeks. To date, there are limited data on the average duration of admission for patients admitted to the EMU for spell classification...

article

Olfactory dysfunction in incidental Lewy body disease and Parkinson's disease

Erika Driver-Dunckley, Charles H. Adler, Joseph G. Hentz, Brittany N. Dugger, more

Parkinsonism and Related Disorders > 2014 > 20 > 11 > 1260-1262

Olfactory dysfunction in Parkinson's disease (PD) is well-established and may represent one of the earliest signs of the disease.The objective of this study was to evaluate the relationship of olfactory dysfunction, using the University of Pennsylvania Smell Identification Test (UPSIT), to clinical and pathological parameters of clinicopathologically diagnosed PD (n = 10), incidental Lewy body disease...

article

Reply: Purkinje cell loss in essential tremor

Holly A. Shill, Charles H. Adler, Joseph G. Hentz

Movement Disorders > 29 > 10 > 1330 - 1331

article

Plaques and tangles as well as Lewy-type alpha synucleinopathy are associated with formed visual hallucinations

Sandra A. Jacobson, Trisha Morshed, Brittany N. Dugger, Thomas G. Beach, more

Parkinsonism and Related Disorders > 2014 > 20 > 9 > 1009-1014

Previous research has linked complex or formed visual hallucinations (VH) to Lewy-type alpha-synucleinopathy (LTS) in neocortical and limbic areas. As Alzheimer's disease pathology often co-occurs with LTS, we questioned whether this pathology – amyloid plaques and neurofibrillary tangles – might also be linked to VH.We performed a semi-quantitative neuropathological study across brainstem, limbic,...

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ABSENCE OF A "WIDOWHOOD EFFECT" ON INCIDENCE OF DEMENTIA IN COGNITIVELY NORMAL RESEARCH SUBJECTS

Bryan Keith Woodruff, Cynthia Stonnington, Dona E.C. Locke, Joseph G. Hentz, more

Alzheimer's & Dementia: The Journal of the Alzheimer's Association > 2014 > 10 > 4 Supplement > P617-P618

article

PARADOXICAL IMPACT OF WIDOWHOOD ON INCIDENCE OF DEMENTIA IN SUBJECTS WITH MILD COGNITIVE IMPAIRMENT

Bryan Keith Woodruff, Cynthia M. Stonnington, Dona E.C. Locke, Joseph G. Hentz, more

Alzheimer's & Dementia: The Journal of the Alzheimer's Association > 2014 > 10 > 4 Supplement > P617

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Search results for: Joseph G. Hentz

Headache characteristics and burden from chronic migraine with medication overuse headache: Cross‐sectional observations from the Medication Overuse Treatment Strategy trial

Lewy body pathology in Alzheimer's disease: A clinicopathological prospective study

Peripheral synucleinopathy in early Parkinson's disease: Submandibular gland needle biopsy findings

A resilience intervention involving mindfulness training for transplant patients and their caregivers

Cortical phosphorylated α‐Synuclein levels correlate with brain wave spectra in Parkinson's disease

Assessing medication role on neuropathological findings in Parkinson's disease

Graph theory network function in Parkinson’s disease assessed with electroencephalography

Peripheral Synucleinopathy in Early Parkinson's Disease: Submandibular Gland Needle Biopsy Findings

Simplified conversion method for unified Parkinson's disease rating scale motor examinations

REM sleep behavior disorder and neuropathology in Parkinson's disease

Arizona Study of Aging and Neurodegenerative Disorders and Brain and Body Donation Program

Quality of life in psychogenic nonepileptic seizures and epilepsy: The role of somatization and alexithymia

The Chitranjan Ranawat Award: Periarticular Injections and Femoral & Sciatic Blocks Provide Similar Pain Relief After TKA: A Randomized Clinical Trial

Neuropathological comparisons of amnestic and nonamnestic mild cognitive impairment

The influence of staffing on diagnostic yield of EMU admissions: A comparison study between two institutions

Olfactory dysfunction in incidental Lewy body disease and Parkinson's disease

Reply: Purkinje cell loss in essential tremor

Plaques and tangles as well as Lewy-type alpha synucleinopathy are associated with formed visual hallucinations

ABSENCE OF A "WIDOWHOOD EFFECT" ON INCIDENCE OF DEMENTIA IN COGNITIVELY NORMAL RESEARCH SUBJECTS

PARADOXICAL IMPACT OF WIDOWHOOD ON INCIDENCE OF DEMENTIA IN SUBJECTS WITH MILD COGNITIVE IMPAIRMENT

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