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Tree‐ring densitometric studies conducted in semi‐arid regions are exceedingly rare. In this study, we evaluate a new maximum latewood density chronology from a collection of Picea purpurea trees growing in semi‐arid northwestern China for climatic reconstruction purposes. We find statistically significant correlations between annual maximum density variations and July–September maximum temperatures...
Imperatorin is a small molecule nature compound isolated from the root of Angelica dahurica, and has been shown to exhibit multiple bioeffector functions, including anti-cancer activity. However, the molecular mechanism underlying imperatorin in suppression of tumor growth is unknown. In this study, we aimed at elucidating the molecular mechanisms underlying imperatorin function and determining the...
Drug resistance is a major reason for therapy failure in cancer. Clitocine is a natural amino nucleoside isolated from mushroom and has been shown to inhibit cancer cell proliferation in vitro. In this study, we observed that clitocine can effectively induce drug-resistant human cancer cell apoptosis in vitro and inhibit tumor xenograft growth in vivo. Clitocine treatment inhibited drug-resistant...
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