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We present an application of mechanistic modeling and nonlinear longitudinal regression in the context of biomedical response‐to‐challenge experiments, a field where these methods are underutilized. In this type of experiment, a system is studied by imposing an experimental challenge, and then observing its response. The combination of mechanistic modeling and nonlinear longitudinal regression has...
Anomalous indications in monitoring equipment onboard U.S. Navy vessels must be handled in a timely manner to prevent catastrophic system failure. The development of sensor data analysis techniques to assist a ship's crew in monitoring machinery and summon required ship-to-shore assistance is of considerable benefit to the Navy. In addition, the Navy has a large interest in the development of distance...
An active approach for failure detection based on the use of minimal auxiliary signals has recently been introduced for linear systems with both additive and model uncertainty. This paper discusses the extension of this approach to nonlinear systems. A nonlinear case study is performed to carefully examine this approach. Evaluation of the performance of the new test signal on the nonlinear system...
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