Search results for: M. Emri

Items from 1 to 20 out of 29 results

article

Valproate treatment normalizes EEG functional connectivity in successfully treated idiopathic generalized epilepsy patients

B. Clemens, S. Puskás, M. Besenyei, N.Zs. Kovács, more

Epilepsy Research > 2014 > 108 > 10 > 1896-1903

To investigate the effect of chronic VPA treatment of EEG functional connectivity in successfully treated idiopathic generalized epilepsy (IGE) patients.19-channel waking, resting-state EEG records of 26 IGE patients were analyzed before treatment (IGE) and after the 90th day of treatment (VPA), in seizure-free condition. Three minutes of artifact-free EEG background activity (without epileptiform...

article

EP-1421: f-MRI signal changes following 3D conformal radiotherapy of GBM patients. Intra-observer variability results

A. Kovacs, M. Emri, G. Opposits, G. Pisak, more

Radiotherapy and Oncology > 2014 > 111 > Supplement 1 > S129

article

Neurophysiology of juvenile myoclonic epilepsy: EEG-based network and graph analysis of the interictal and immediate preictal states

B. Clemens, S. Puskás, M. Besenyei, T. Spisák, more

Epilepsy Research > 2013 > 106 > 3 > 357-369

The neuronal mechanisms of enduring seizure propensity and seizure precipitation in juvenile myoclonic epilepsy (JME) are not known. We investigated these issues, within the framework of the “network concept” of epilepsy.Design1: 19, unmedicated JME patients were compared with nineteen, age-, and sex-matched normal control persons (NC). A total of 120s, artifact-free, paroxysm-free, eyes-closed, resting...

article

Remission of benign epilepsy with rolandic spikes: An EEG-based connectivity study at the onset of the disease and at remission

B. Clemens, S. Puskás, M. Besenyei, T. Spisák, more

Epilepsy Research > 2013 > 106 > 1-2 > 128-135

The neuronal mechanisms of remission of epilepsy are not known. Based on the principles of the “network theory of epilepsy” we postulated the existence of abnormal cortico-cortical interactions at the onset of epilepsy (Hypothesis-1), and postulated that remission is associated with the decrease or disappearance of the abnormal quantitative EEG findings (Hypothesis-2).Four children with benign epilepsy...

chapter

Reference database driven statistical analysis of automated frameless CT-MRI registration developed for radiosurgical investigations

G. Opposits, S.A. Kis, T. Spisak, E. Berenyi, more

2012 IEEE Nuclear Science Symposium and Medical Imaging Conference Record (NSS/MIC) > 2780 - 2782

2012 IEEE Nuclear Science Symposium and Medical Imaging Conference (2012 NSS/MIC)

The aims of this study were (1) to describe statistically the fluctuation of the goodness of automated CT-MRI registration method (2) to evaluate a numerical parameter, scaled to [0,1] interval (lambda), for characterizing the population level accuracy of any automated CT-MRI registration algorithm on voxel similarity basis. The population level distribution of cross-correlation values between the...

article

EEG-LORETA endophenotypes of the common idiopathic generalized epilepsy syndromes

B. Clemens, S. Puskás, M. Besenyei, M. Emri, more

Epilepsy Research > 2012 > 99 > 3 > 281-292

We tested the hypothesis that the cortical areas with abnormal local EEG synchronization are dissimilar in the three common idiopathic generalized epilepsy (IGE) phenotypes: IGE patients with absence seizures (ABS), juvenile myoclonic epilepsy (JME) and epilepsy with generalized tonic–clonic seizures exclusively (EGTCS).Groups of unmedicated ABS, JME and EGTCS patients were investigated. Waking EEG...

article

EEG background activity is abnormal in the temporal and inferior parietal cortex in benign rolandic epilepsy of childhood: A LORETA study

M. Besenyei, E. Varga, I. Fekete, S. Puskás, more

Epilepsy Research > 2012 > 98 > 1 > 44-49

Benign rolandic epilepsy of childhood (BERS) is an epilepsy syndrome with presumably genetic-developmental etiology. The pathological basis of this syndrome is completely unknown. We postulated that a developmental abnormality presumably results in abnormal EEG background activity findings.20 children with typical BERS and an age- and sex-matched group of healthy control children underwent EEG recording...

chapter

Analysis of the minimum detectable activity of a small animal scanner

I. Lajtos, M. Emri, S.A. Kis, G. Opposits, more

2011 IEEE Nuclear Science Symposium Conference Record > 3839 - 3841

2011 IEEE Nuclear Science Symposium and Medical Imaging Conference (2011 NSS/MIC)

Studies in nuclear medicine frequently require the measurement of very low activity lesions in a background region. The detectability depends on a number of properties of the lesion (size, shape, signal amplitude), the background (quantum noise from the imaging process and anatomical variability) and the observer performance. We investigated the differences between the human and mathematical model...

article

EEG functional connectivity of the intrahemispheric cortico-cortical network of idiopathic generalized epilepsy

B. Clemens, S. Puskás, M. Bessenyei, M. Emri, more

Epilepsy Research > 2011 > 96 > 1-2 > 11-23

Intrahemispheric, cortico-cortical EEG functional connectivity (fC) was investigated in untreated patients with idiopathic generalized epilepsy (IGE) in this explorative study.Group comparison was carried out between 19, drug-naive IGE patients and 19, matched healthy persons. 90ÿ2s of 19 channels waking, interictal background EEG signal (without epileptiform potentials) were processed to the LORETA...

chapter

Analysis of the minimum detectable activity of a small animal scanner

I Lajtos, M Emri, S A Kis, G Opposits, more

IEEE Nuclear Science Symposuim & Medical Imaging Conference > 2224 - 2227

2010 IEEE Nuclear Science Symposium and Medical Imaging Conference (2010 NSS/MIC)

The examination of small animals using high resolution in-vivo imaging methods is a crucial tool in pharmaceutical research projects. These type of studies frequently require the measurement of very low activity lesions in a background region or high activity body parts for instance in case of dynamic investigations. To suffice these demands, two independent qualities of the PET scanner need to be...

chapter

Performance test of the MiniPET-II small animal scanner according to the NEMA NU-4 standard

S.A. Kis, I. Lajtos, M. Emri, L. Tron, more

2009 IEEE Nuclear Science Symposium Conference Record (NSS/MIC) > 3185 - 3189

2009 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC 2009)

A full ring small animal PET camera (MiniPET-II) has been built in our institute as part of an R+D project. In this work we determined the performance parameters of the MiniPET-II scanner. The measurements and data evaluation for this purpose were based on the National Electrical Manufacturers Association (NEMA) NU-4 standards. The spatial resolution varies between 1.4 to 2.1 mm from central to 25...

chapter

Distributed online coincidence detection using IP multicast for the miniPET-II detector

J. Imrek, G. Hegyesi, G. Kalinka, J. Molnar, more

2009 IEEE Nuclear Science Symposium Conference Record (NSS/MIC) > 2434 - 2436

2009 IEEE Nuclear Science Symposium and Medical Imaging Conference (NSS/MIC 2009)

We report on a distributed online coincidence detection implementation that we have recently added to the miniPET-II small animal PET scanner. The implementation uses standard Ethernet and IP multicasting techniques, therefore no architectural changes were necessary to the existing system. For 2D reconstruction the implementation scales with the number of detectors in the system, so it can be used...

chapter

Internals and evaluation of the miniPET-II detector module

J. Imrek, G. Hegyesi, G. Kalinka, J. Molnar, more

2007 IEEE Nuclear Science Symposium Conference Record > 4 > 2930 - 2932

2007 IEEE Nuclear Science Symposium

We report on the architecture of the system-on- module (SoM) developed by our group for miniPET-II, the second version of our small animal PET scanner. The paper describes the hardware and software implementation details of the SoM we realized inside the miniPET-II detector module, the embedded Linux operation system, and the the initial results of bandwidth test measurements on the assembled SoM...

article

Full 3-D cluster-based iterative image reconstruction tool for a small animal PET camera

I. Valastyán, J. Imrek, J. Molnár, D. Novák, more

Nuclear Inst. and Methods in Physics Research, A > 2007 > 571 > 1-2 > 219-222

Iterative reconstruction methods are commonly used to obtain images with high resolution and good signal-to-noise ratio in nuclear imaging. The aim of this work was to develop a scalable, fast, cluster based, fully 3-D iterative image reconstruction package for our small animal PET camera, the miniPET. The reconstruction package is developed to determine the 3-D radioactivity distribution from list...

article

Comparison of Monte Carlo simulated and measured performance parameters of miniPET scanner

S.A. Kis, M. Emri, G. Opposits, T. Bükki, more

Nuclear Inst. and Methods in Physics Research, A > 2007 > 571 > 1-2 > 449-452

In vivo imaging of small laboratory animals is a valuable tool in the development of new drugs. For this purpose, miniPET, an easy to scale modular small animal PET camera has been developed at our institutes. The system has four modules, which makes it possible to rotate the whole detector system around the axis of the field of view. Data collection and image reconstruction are performed using a...

chapter

Software development framework supporting multimodal tomographic imaging

M. Emri, G. Opposits, S.A. Kis, L. Tron, more

2006 IEEE Nuclear Science Symposium Conference Record > 3 > 1857 - 1859

2006 IEEE Nuclear Science Symposium Conference Record

Engineers specialized in multimodal tomography regularly face a wide scale of programming tasks requiring an integrated software system to ensure cost efficiency. Accordingly, a software development framework has been worked out comprising libraries for cluster-based data acquisition, image reconstruction, management of data files and complex multimodal volumetric visualization. This framework enabled...

chapter

Development of an Improved Detector Module for miniPET-II

J. Imrek, G. Hegyesi, G. Kalinka, J. Molnar, more

2006 IEEE Nuclear Science Symposium Conference Record > 5 > 3037 - 3040

2006 IEEE Nuclear Science Symposium Conference Record

We present a new detector module developed for miniPET-II, the second generation of the miniPET small animal PET scanners. The improved module features new hardware components for better performance: LySO crystal material, increased number of crystal segments, Hamamatsu H9500 PSPMT, Xilinx Virtex-4 FPGA and Gigabit Ethernet. However, the principle of operation is the same: no hardware coincidence...

article

A SPECT demonstrator—revival of a gamma camera

I. Valastyán, A. Kerek, J. Molnár, D. Novák, more

Nuclear Inst. and Methods in Physics Research, A > 2006 > 563 > 1 > 274-277

A gamma camera has been updated and converted to serve as a demonstrator for educational purposes. The gantry and the camera head were the only part of the system that remained untouched. The main reason for this modernization was to increase the transparency of the gamma camera by partitioning the different logical building blocks of the system and thus providing access for inspection and improvements...

article

Ethernet Based Distributed Data Acquisition System for a Small Animal PET

G. Hegyesi, J. Imrek, G. Kalinka, J. Molnar, more

IEEE Transactions on Nuclear Science > 2006 > 53 > 4-2 > 2112 - 2117

We report on the design of a small animal PET scanner being developed at our institutes. The existing setup is the first version of the miniPET machine consisting of four detector modules. Each detector module consists of an 8times8 LSO scintillator crystal block, a position sensitive photomultiplier, a digitizer including a digital signal processing board and an Ethernet interface board. There is...

article

Development of an FPGA-Based Data Acquisition Module for Small Animal PET

J. Imrek, D. Novak, G. Hegyesi, G. Kalinka, more

IEEE Transactions on Nuclear Science > 2006 > 53 > 5-1 > 2698 - 2703

We report on the design of a data acquisition (DAQ) module for a small animal PET camera developed at our institutes. During the design an important guideline was to develop a system which is built up from strictly identical DAQ modules, and which has no built-in hardware limitation on the maximum number of modules. The developed DAQ module comprises of an LSO scintillator crystal block, a position...

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INFONA - science communication portal

Search results for: M. Emri

Valproate treatment normalizes EEG functional connectivity in successfully treated idiopathic generalized epilepsy patients

EP-1421: f-MRI signal changes following 3D conformal radiotherapy of GBM patients. Intra-observer variability results

Neurophysiology of juvenile myoclonic epilepsy: EEG-based network and graph analysis of the interictal and immediate preictal states

Remission of benign epilepsy with rolandic spikes: An EEG-based connectivity study at the onset of the disease and at remission

Reference database driven statistical analysis of automated frameless CT-MRI registration developed for radiosurgical investigations

EEG-LORETA endophenotypes of the common idiopathic generalized epilepsy syndromes

EEG background activity is abnormal in the temporal and inferior parietal cortex in benign rolandic epilepsy of childhood: A LORETA study

Analysis of the minimum detectable activity of a small animal scanner

EEG functional connectivity of the intrahemispheric cortico-cortical network of idiopathic generalized epilepsy

Analysis of the minimum detectable activity of a small animal scanner

Performance test of the MiniPET-II small animal scanner according to the NEMA NU-4 standard

Distributed online coincidence detection using IP multicast for the miniPET-II detector

Internals and evaluation of the miniPET-II detector module

Full 3-D cluster-based iterative image reconstruction tool for a small animal PET camera

Comparison of Monte Carlo simulated and measured performance parameters of miniPET scanner

Software development framework supporting multimodal tomographic imaging

Development of an Improved Detector Module for miniPET-II

A SPECT demonstrator—revival of a gamma camera

Ethernet Based Distributed Data Acquisition System for a Small Animal PET

Development of an FPGA-Based Data Acquisition Module for Small Animal PET

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