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Background: Epidemiological studies indicate there is low incidence of colon cancer in the South Pacific islands, including Fiji, West Samoa, and Vanuatu. Cancer incidence has been shown to be inversely associated with kava (Piper methysticum G. Forst.) ingestion. Hypothesis/Purpose: Kava prepared traditionally will inhibit the growth of human cancer cells. This investigation entails preparation and...
Prestress in actin filaments plays an important role in the stability of cells and it strongly influences the cell stiffness. In this paper, we present a simple polygonal cytoskeleton model to study the influence of cell prestress. The existence of prestress is shown to facilitate cytoskeletal integrity. Remarkably, the optimum prestress is computed to be several kPa of extension, which is comparable...
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