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Precise control of DNA base pairing has rapidly developed into a field full of diverse nanoscale structures and devices that are capable of automation, performing molecular analyses, mimicking enzymatic cascades, biosensing, and delivering drugs. This DNA‐based platform has shown the potential of offering novel therapeutics and biomolecular analysis but will ultimately require clever modification...
DNA nanostructures offer new opportunities for diagnostics, therapeutics and biomolecular analysis. For that purpose, they require special modifications and functionalities. In article number 1805386, Megan E. Kizer, Robert J. Linhardt, Arun Richard Chandrasekaran, and Xing Wang discuss the properties needed to make DNA nanostructures applicable to in vitro and in vivo applications by drawing analogies...
With the emergence of “super bacteria” that are resistant to antibiotics, e.g., methicillin-resistant Staphylococcus aureus, novel antimicrobial therapies are needed to prevent associated hospitalizations and deaths. Bacteriophages and bacteria use cell lytic enzymes to kill host or competing bacteria, respectively, in natural environments. Taking inspiration from nature, we have employed a cell lytic...
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