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Background and purpose: Two novel fractionation schedules for whole-brain irradiation were applied to patients with brain metastases. Both schedules were aimed at reduction of treatment time, whereby tumour control should be increasing with the application of a higher total dose (schedule 2).Materials and methods: We applied 2 2.5 Gy/day to a total dose of 30 Gy (schedule 1) or 2 1.8 Gy/day...
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