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Microfluidics technology has been exploited in single cell study because of its ability to manipulate particles and control over culture conditions. Two drawbacks of the existing studies are that (1) they require large supporting equipment like an incubator and a syringe pump; which involves more culture media volume, and that (2) the trapped cells are isolated from one another that cell interaction...
This paper discuss drug concentration measurement based on Raman spectroscopy of tear fluids with paper substrates for on-site therapeutic drug monitoring (TDM). We focus on tear fluids as alternative specimens to blood for minimally-invasive TDM. By using paper substrates, specimen collection and measurement based on surface enhanced Raman spectroscopy will be performed easily and inexpensively....
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