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Background: The emergence of HMG-CoA-reductase inhibitors (''statins'') as staples in the treatment of hyperlipidemia is due to their superior efficacy and tolerability relative to other classes of lipid regulators. Paradoxically, however, two of the three most recent members of this class (fluvastatin and cerivastatin) are less effective in lowering LDL levels than previously marketed statins, and...
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