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Our studies concern the mechanisms of synaptic transmission and integration in the basal ganglia network, using immunotoxin-mediated cell targeting. We generated transgenic mice that expressed the human interleukin-2 receptor (hIL-2R)/GFP fusion protein under the control of the mGluR2 promoter. The immunotoxin that was composed of the monoclonal hIL-2R antibody fused to bacterial toxin was injected...
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