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Gastrointestinal side effects such as nausea and abdominal pain are associated with the oral ingestion of 8-methoxypsoralen (8-MOP), including the liquid and crystalline formulations that are currently available. In an open pilot study, 8-MOP rectal suppositories were given to six patients with psoriasis vulgaris who had experienced significant nausea and/or abdominal pain with the oral liquid form...
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