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Study Type – Prognosis (cohort)Level of Evidence 2aWhat's known on the subject? and What does the study add?Men fail active surveillance for a variety of reasons; however, no single reliable biomarker has been found to date which will identify these men from the outset. We know that there are about 35 prostate cancer risk alleles which have been discovered to influence risk of prostate cancer, from...
Study Type – Therapy (case series)Level of Evidence 4What's known on the subject? and What does the study add?High‐grade prostate cancers are associated with poor disease‐specific outcomes. A proportion of these tumours produce little PSA.This study demonstrates that among Gleason 8–10 prostate cancers, some of the worst survival outcomes are associated with the lowest PSA levels.
OBJECTIVE• To assess...
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