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Propionate of vitamin A (PVA) is a highly instable and poorly water-soluble molecule which is of real interest for therapeutics. 1:1 γCD/PVA and 2:1 βCD/PVA inclusion complexes are formed. A stability study using NMR and HPLC indicated that βCD induced an accelerated degradation of PVA but, conversely γCD could protect it efficiently for many months. A very stable and soluble complex can be formed...