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Endometriose ist mit einer Prävalenzrate von 10–15% eine häufige gynäkologische Erkrankung von Frauen im reproduktionsfähigen Alter. Neben genetischen, immunologischen und Umweltfaktoren spielt auch eine gestörte Angiogenese eine entscheidende Rolle in der Ausbildung der Erkrankung. Da Endometrioseherde eine ausgeprägte Blutversorgung für ihr Überleben und ihre Entwicklung benötigen, sind sie—analog...
Objective: To provide a review of the humoral and cellular immunology of endometriosis and to discuss the rationale for future approaches to diagnosis and treatment.Design: Literature survey.Result(s): Defective immunosurveillance in women who are destined to develop endometriosis may allow for the survival of ectopic endometrial tissue. The evidence includes endometrial cell resistance to apoptosis,...
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