Search results for: Xia Wu

Items from 1 to 20 out of 746 results

article

Comparative and functional analysis unveils the contribution of photoperiod to DNA methylation, sRNA accumulation, and gene expression variations in short‐day and long‐day grasses

Xia Wu, Siyi Chen, Feng Lin, Fahad Muhammad, more

The Plant Journal > 118 > 6 > 1955 - 1971

Photoperiod employs complicated networks to regulate various developmental processes in plants, including flowering transition. However, the specific mechanisms by which photoperiod affects epigenetic modifications and gene expression variations in plants remain elusive. In this study, we conducted a comprehensive analysis of DNA methylation, small RNA (sRNA) accumulation, and gene expressions under...

article

A Universal and Programmable Platform based on Fluorescent Peptide‐Conjugated Probes for Detection of Proteins in Organelles of Living Cells

Xia Wu, Jing‐Jing Hu, Chong Duan, Rui Liu, more

Angewandte Chemie International Edition > 63 > 17 > n/a - n/a

Realizing protein analysis in organelles of living cells is of great significance for developing diagnostic and therapeutic methods of diseases. Fluorescent‐labeled antibodies with well imaging performance and high affinity are classical biochemical tools for protein analysis, while due to the inability to effectively enter into cells, not to mention organelles and the uncontrollable reaction sites...

article

A Universal and Programmable Platform based on Fluorescent Peptide‐Conjugated Probes for Detection of Proteins in Organelles of Living Cells

Xia Wu, Jing‐Jing Hu, Chong Duan, Rui Liu, more

Angewandte Chemie > 136 > 17 > n/a - n/a

article

Effect of endoscopic mucosal resection and endoscopic submucosal dissection on postoperative wound complications in patients with gastric cancer: A meta‐analysis

Xiaoyun Liu, Xia Wu, Wenjun Fan

International Wound Journal > 21 > 4 > n/a - n/a

Endoscopic submucosa dissection (ESD) allows complete excision of the whole lesion, which results in a higher percentage of complete excision and an improved quality of life by minimizing the amount of excision as opposed to an endoscopic mucosal resection (EMR). Although ESD is now being carried out in the majority of hospitals, ESD's possible complications (such as trauma and perforation) have given...

article

Aggregation‐Induced Emission Photosensitizer‐Armored Magnetic Nanoparticles for Sepsis Treatment: Combating Multidrug‐Resistant Bacteria and Alleviating Inflammation

Jia‐Li Wang, Yuan Chen, Jia‐Xing Song, Bing‐Wei Guo, more

Advanced Functional Materials > 34 > 10 > n/a - n/a

Sepsis, a life‐threatening condition stemming from an uncontrolled host immune response to bacterial infections, continues to impose a significant global burden with high morbidity and mortality. Addressing the challenges posed by antimicrobial resistance and uncontrollable inflammation remains a challenge in sepsis treatment. Moreover, traditional antibacterial materials have low bacterial trapping...

article

Prior‐guided individualized thalamic parcellation based on local diffusion characteristics

Chaohong Gao, Xia Wu, Yaping Wang, Gang Li, more

Human Brain Mapping > 45 > 4 > n/a - n/a

Comprising numerous subnuclei, the thalamus intricately interconnects the cortex and subcortex, orchestrating various facets of brain functions. Extracting personalized parcellation patterns for these subnuclei is crucial, as different thalamic nuclei play varying roles in cognition and serve as therapeutic targets for neuromodulation. However, accurately delineating the thalamic nuclei boundary at...

article

Risk factors of cognitive frailty in elderly chronic obstructive pulmonary disease patients and its implication for death: a cohort study

Xia Wu, Kehan Huang, Tingting Jiang, Huiqin Yu

Psychogeriatrics > 24 > 2 > 295 - 302

Backgrounds Cognitive frailty, a clinical syndrome with physical frailty and cognitive impairment, leads to mortality and other adverse health outcomes in older adults. This study aimed to investigate the prevalence of cognitive frailty, and its influencing factors, and follow its impact on short‐term mortality in elderly chronic obstructive pulmonary disease patients, to provide a theoretical scientific...

article

Using machine learning to predict the bleeding risk for patients with cardiac valve replacement treated with warfarin in hospitalized

Yixing Hu, Xuemeng Zhang, Meng Wei, Tongtong Yang, more

Pharmacoepidemiology and Drug Safety > 33 > 2 > n/a - n/a

Background Distinguishing warfarin‐related bleeding risk at the bedside remains challenging. Studies indicate that warfarin therapy should be suspended when international normalized ratio (INR) ≥ 4.5, or it may sharply increase the risk of bleeding. We aim to develop and validate a model to predict the high bleeding risk in valve replacement patients during hospitalization. Method Cardiac valve...

article

Piperine improves levodopa availability in the 6‐OHDA‐lesioned rat model of Parkinson's disease by suppressing gut bacterial tyrosine decarboxylase

Xiaolu Hu, Lan Yu, Yatong Li, Xiaoxi Li, more

CNS Neuroscience & Therapeutics > 30 > 2 > n/a - n/a

Aim Tyrosine decarboxylase (TDC) presented in the gut‐associated strain Enterococcus faecalis can convert levodopa (L‐dopa) into dopamine (DA), and its increased abundance would potentially minimize the availability and efficacy of L‐dopa. However, the known human decarboxylase inhibitors are ineffective in this bacteria‐mediated conversion. This study aims to investigate the inhibition of piperine...

article

Efficacy of adalimumab combined with Tripterygium wilfordii Hook F in the treatment of patient with rheumatoid arthritis: A multicenter, open‐label, randomized‐controlled trial

Feng Luo, Shuo‐Yan Gau, Yu‐xia Wu, Hou‐li Liao, more

International Journal of Rheumatic Diseases > 27 > 1 > n/a - n/a

Objectives To evaluate the efficacy and safety of adalimumab (ADA) combined with Tripterygium wilfordii Hook F (TwHF) in the treatment of methotrexate (MTX)‐inadequate response patients with rheumatoid arthritis (RA). Methods In this multicenter, open‐label, randomized controlled clinical trial, 64 RA patients with inadequate response to MTX were 1:1 randomly assigned into treatment or control...

article

Aflibercept Loaded Eye‐Drop Hydrogel Mediated with Cell‐Penetrating Peptide for Corneal Neovascularization Treatment

Jianan Zhou, Yuting Cai, Tingting Li, Haixiang Zhou, more

Small > 20 > 2 > n/a - n/a

Corneal neovascularization (CoNV) is a major cause of visual impairment worldwide. Currently, available treatment options have limited efficacy and are associated with adverse effects due to biological barriers and clearance mechanisms. To address this challenge, a novel topical delivery system is developed—Gel 2_1&Eylea—an aflibercept‐loaded eye‐drop hydrogel mediated with cell‐penetrating peptide...

article

SNHG16/miR‐205/HDAC5 is involved in the progression of renal fibrosis

Yingdan Zhao, Hanqing Wang, Yunhai Tang, Juan Wang, more

Journal of Biochemical and Molecular Toxicology > 38 > 1 > n/a - n/a

Renal interstitial fibrosis (RIF) represents an irreversible and progressive pathological manifestation of chronic renal disease, which ultimately leads to end‐stage renal disease. Long noncoding RNAs (lncRNAs) have been suggested to be involved in the progression of RIF. Small nucleolar RNA host gene 16 (SNHG16), a member of lncRNAs, has been found to be involved in the progression of pulmonary fibrosis...

article

Washed microbiota transplantation for Clostridioides difficile infection: A national multicenter real‐world study

Xia Wu, Ru Jun Ai, Jie Xu, Quan Wen, more

Journal of Digestive Diseases > 24 > 10 > 540 - 549

Objectives Fecal microbiota transplantation (FMT) has been recommended for the treatment of recurrent Clostridioides difficile infection (CDI). We aimed to evaluate the therapeutic efficacy and safety of washed microbiota transplantation (WMT), a new method of FMT, for CDI across various medical settings. Methods This multicenter real‐world cohort study included CDI patients undergoing WMT. The...

article

The interaction and mediation effects between the host genetic factors and Epstein–Barr virus VCA‐IgA in the risk of nasopharyngeal carcinoma

Hua Diao, Wen‐Qiong Xue, Tong‐Min Wang, Da‐Wei Yang, more

Journal of Medical Virology > 95 > 11 > n/a - n/a

Previous studies have demonstrated strong associations between host genetic factors and Epstein–Barr virus (EBV) VCA‐IgA with the risk of nasopharyngeal carcinoma (NPC). However, the specific interplay between host genetics and EBV VCA‐IgA on NPC risk is not well understood. In this two‐stage case–control study (N = 4804), we utilized interaction and mediation analysis to investigate the interplay...

article

How sleep disturbance is associated with Chinese police officers' job satisfaction: A moderated mediation model

Zhi Ye, Yinyi Wang, Xia Wu, Lihua Chen

Stress and Health > 39 > 4 > 902 - 911

Tasked with a wide variety of duties, police officers often encounter stressful situations and suffer from sleep disturbance. Previous studies have found that police officers with sleep disturbance generally reported lower levels of job satisfaction; however, the psychological mechanisms by which sleep disturbance is associated with job satisfaction are still relatively underexplored. This study investigated...

article

The Membrane Phospholipidomics Research of Oxidatively Damaged INS‐1 Pancreatic Beta Cells Intervened by the Effective Constituents of Anemarrhenae Asphodeloides Rhizoma

Luming Xie, Jing Zhang, Pingyan Zeng, Yifan Feng, more

Chemistry & Biodiversity > 20 > 8 > n/a - n/a

The rhizoma of Anemarrhenae asphodeloides has a long history of hypoglycemic use in Chinese traditional medicine. In this article, 400 μmol/L H₂O₂ induced normal INS‐1 pancreatic beta cells to establish experimental model of oxidative damage. Quercetin was used as a positive drug, and mangiferin and its ethanolic extract were selected as therapeutic agents in an oxidative damage model to evaluate...

article

Research Progress on the Structural Modification of Magnolol and Honokiol and the Biological Activities of Their Derivatives

M. M. Ming‐Xin Guo, Xia Wu, Yi‐Fan Feng, Zhi‐Qiang Hu

Chemistry & Biodiversity > 20 > 8 > n/a - n/a

Magnolol and Honokiol are the primary active components that have been identified and extracted from Magnolia officinalis, and several investigations have demonstrated that they have significant pharmacological effects. Despite their therapeutic benefits for a wide range of illnesses, research on and the implementation of these compounds have been hindered by their poor water solubility and low bioavailability...

article

Phosphine‐Triggered Structural Defects in Au₄₄ Homologues Boost Electrocatalytic CO₂ Reduction

Shengli Zhuang, Dong Chen, Wai‐Pan Ng, Li‐Juan Liu, more

Angewandte Chemie International Edition > 62 > 33 > n/a - n/a

The systematic induction of structural defects at the atomic level is crucial to metal nanocluster research because it endows cluster‐based catalysts with highly reactive centers and allows for a comprehensive investigation of viable reaction pathways. Herein, by substituting neutral phosphine ligands for surface anionic thiolate ligands, we establish that one or two Au₃ triangular units can be successfully...

article

Phosphine‐Triggered Structural Defects in Au₄₄ Homologues Boost Electrocatalytic CO₂ Reduction

Shengli Zhuang, Dong Chen, Wai‐Pan Ng, Li‐Juan Liu, more

Angewandte Chemie > 135 > 33 > n/a - n/a

article

Metabolic profiles and correlation with surgical outcomes in mesial versus neocortical temporal lobe epilepsy

Hao‐yue Zhu, Yong‐xiang Tang, Ling Xiao, Shi‐rui Wen, more

CNS Neuroscience & Therapeutics > 29 > 9 > 2656 - 2665

Aims Differentiating mesial temporal lobe epilepsy (MTLE) and neocortical temporal lobe epilepsy (NTLE) remains challenging. Our study characterized the metabolic profiles between MTLE and NTLE and their correlation with surgical prognosis using ¹⁸F‐FDG‐PET. Methods A total of 137 patients with intractable temporal lobe epilepsy (TLE) and 40 age‐matched healthy controls were recruited. Patients...

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INFONA - science communication portal

Search results for: Xia Wu

Comparative and functional analysis unveils the contribution of photoperiod to DNA methylation, sRNA accumulation, and gene expression variations in short‐day and long‐day grasses

A Universal and Programmable Platform based on Fluorescent Peptide‐Conjugated Probes for Detection of Proteins in Organelles of Living Cells

A Universal and Programmable Platform based on Fluorescent Peptide‐Conjugated Probes for Detection of Proteins in Organelles of Living Cells

Effect of endoscopic mucosal resection and endoscopic submucosal dissection on postoperative wound complications in patients with gastric cancer: A meta‐analysis

Aggregation‐Induced Emission Photosensitizer‐Armored Magnetic Nanoparticles for Sepsis Treatment: Combating Multidrug‐Resistant Bacteria and Alleviating Inflammation

Prior‐guided individualized thalamic parcellation based on local diffusion characteristics

Risk factors of cognitive frailty in elderly chronic obstructive pulmonary disease patients and its implication for death: a cohort study

Using machine learning to predict the bleeding risk for patients with cardiac valve replacement treated with warfarin in hospitalized

Piperine improves levodopa availability in the 6‐OHDA‐lesioned rat model of Parkinson's disease by suppressing gut bacterial tyrosine decarboxylase

Efficacy of adalimumab combined with Tripterygium wilfordii Hook F in the treatment of patient with rheumatoid arthritis: A multicenter, open‐label, randomized‐controlled trial

Aflibercept Loaded Eye‐Drop Hydrogel Mediated with Cell‐Penetrating Peptide for Corneal Neovascularization Treatment

SNHG16/miR‐205/HDAC5 is involved in the progression of renal fibrosis

Washed microbiota transplantation for Clostridioides difficile infection: A national multicenter real‐world study

The interaction and mediation effects between the host genetic factors and Epstein–Barr virus VCA‐IgA in the risk of nasopharyngeal carcinoma

How sleep disturbance is associated with Chinese police officers' job satisfaction: A moderated mediation model

The Membrane Phospholipidomics Research of Oxidatively Damaged INS‐1 Pancreatic Beta Cells Intervened by the Effective Constituents of Anemarrhenae Asphodeloides Rhizoma

Research Progress on the Structural Modification of Magnolol and Honokiol and the Biological Activities of Their Derivatives

Phosphine‐Triggered Structural Defects in Au₄₄ Homologues Boost Electrocatalytic CO₂ Reduction

Phosphine‐Triggered Structural Defects in Au₄₄ Homologues Boost Electrocatalytic CO₂ Reduction

Metabolic profiles and correlation with surgical outcomes in mesial versus neocortical temporal lobe epilepsy

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