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A validation method is a key element in both the elaboration of reference methods and the assessment of a laboratory's competence in producing reliable analytical data. The aim of the study was to validate the GC method (according to Marcus and Sherma), which is used in determining 8-α-hydroxymutilin in a biological matrix (swine tissues: liver and muscles). The fundamental parameters for validation,...
Tiamulin, a semi-synthetic antibiotic agent, is exclusively used in veterinary medicine and is rapidly distributed in the body and intensively metabolized in the liver. The aim of the study was to estimate the residue levels of tiamulin metabolite in pigs. tissues after oral and intramuscular administration. The experiment was carried out on 38 pbz breed weaners, divided into two groups. One of the...
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