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Effects of nanosized (<100nm) titanium dioxide (TiO 2 ) particles on fish neutrophils and immune gene expression was investigated using the fathead minnow (Pimpehales promelas). Expanded use of TiO 2 in the cosmetic industry has increased the potential exposure risk to aquatic ecosystems and human health. Effects of nano-TiO 2 on neutrophil function of the fathead minnow...
With the development of the technique of DNA chips, more and more experiments data can be gained. Genes exhibiting similar patterns are often functionally related, which is very helpful for the research on analyzing the underlying mechanisms of metabolic and regulatory networks in the cell. But the fact that the correlated part is entangled with the unrelated part in the data, and the data is usually...
Gene expression data analysis is very important for the research on gene regulatory mechanisms. Genes which exhibit similar patterns are often functionally related. In this paper a novel bicluster detection method is proposed. Its advantage lies in it can not only make use of the traditional data clustering methods, but also form a systemic architecture. The whole processing procedure can be divided...
Cluster analysis is an important tool for discovering the structures and patterns hidden in gene expression data. In this paper, a new algorithm for clustering gene expression profiles is proposed. In this method, we find natural clusters in the data based on a competitive learning strategy. Using partially known modes as constraints in our method, we reduce the sensitivity of the clustering procedure...
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